IL-TIF Chemical Properties

storage temp. 

-20°C

form 

lyophilized

color 

white to off-white

biological source

mouse

Safety Information

WGK Germany 

3

IL-TIF Usage And Synthesis

General Description

IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10Rb/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant murine IL-22 is a 16.8 kDa non-disulfide-linked monomeric protein containing of two 147 amino acid polypeptide chains.

Biochem/physiol Actions

IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Recombinant murine IL-22 is a 16.8 kDa non-disulfide-linked monomeric protein containing of two 147 amino acid polypeptide chains.

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