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(S)-3-Hydroxypyrrolidine hydrochloride

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(S)-3-Hydroxypyrrolidine hydrochloride Basic information

Product Name:
(S)-3-Hydroxypyrrolidine hydrochloride
Synonyms:
  • (S)-PYRROLIDIN-3-OL HCL
  • (S)-PYRROLIDINE-3-OL HYDROCHLORIDE
  • TIMTEC-BB SBB004272
  • (S)-3-HYDROXY PYRROLIDINE HCL
  • (S)-3-HYDROXYPYRROLIDINE HYDROCHLORIDE
  • (S)-(-)-3-PYRROLIDINOL HYDROCHLORIDE
  • (S)-3-PYRROLIDINOL HYDROCHLORIDE
  • 3-PYRROLIDINOL, HYDROCHLORIDE, (3S)
CAS:
122536-94-1
MF:
C4H10ClNO
MW:
123.58
EINECS:
672-315-7
Product Categories:
  • Chiral chemicals
  • Benzenes
  • pharmacetical
  • Pyrrole&Pyrrolidine&Pyrroline
  • chiral
  • Heterocyclic Compounds
  • Alcohols and Derivatives
  • Intermediate
Mol File:
122536-94-1.mol
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(S)-3-Hydroxypyrrolidine hydrochloride Chemical Properties

Melting point:
104-107°C
Boiling point:
108-110℃/8mm
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Sparingly), Methanol (Slightly)
form 
Solid
color 
Off-White to Pale Beige
Stability:
Hygroscopic
CAS DataBase Reference
122536-94-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
-36/37/38
Safety Statements 
26-37
HS Code 
29339900
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(S)-3-Hydroxypyrrolidine hydrochloride Usage And Synthesis

Chemical Properties

almost white crystalline powder

Uses

(S)-3-Hydroxypyrrolidine Hydrochloride is a useful intermediate for the synthesis of Asimadoline Hydrochlorine (A788250), used in the treatment of IBS, a disorder associated with pain and altered bowel function.

(S)-3-Hydroxypyrrolidine hydrochloride Preparation Products And Raw materials

Raw materials

EtanolSodium hydroxideHydrochloric acidEthyl acetateMethanolTetrahydrofuranDichloromethaneAcetic acid glacialPETROLEUM ETHERLithium aluminium hydrideSodium borohydrideAcetyl chlorideCalcium chlorideBenzylamineHEAVY DISTILLATEL(-)-Malic acid

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(S)-3-Hydroxypyrrolidine hydrochloride(122536-94-1)Related Product Information