Basic information Safety Supplier Related

H-GLY-PRO-ARG-PRO-NH2

Basic information Safety Supplier Related

H-GLY-PRO-ARG-PRO-NH2 Basic information

Product Name:
H-GLY-PRO-ARG-PRO-NH2
Synonyms:
  • H-GLY-PRO-ARG-PRO-NH2
  • GLY-PRO-ARG-PRO AMIDE PEPTIDE
  • H2N-GPRP-AMIDE
  • GPRP-NH2
  • gly-pro-arg-pro amide
  • gly-pro-arg-pro amide acetate
  • H-Gly-Pro-Arg-Pro-NH acetate salt
  • H-Gly-Pro-Arg-Pro-NH2/GPRP-NH2
CAS:
126047-75-4
MF:
C18H32N8O4
MW:
424.5
Product Categories:
  • Clotting FactorsPeptides for Cell Biology
  • Clotting InhibitorsProteins and Derivatives
  • Blood
  • Coagulation Proteins and Reagents
  • Extracellular Matrix Peptides (ECM)
  • Immune Cell Signaling and Blood
  • Plasma&Blood Proteins
Mol File:
126047-75-4.mol
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H-GLY-PRO-ARG-PRO-NH2 Chemical Properties

storage temp. 
-20°C
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Safety Information

WGK Germany 
3
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H-GLY-PRO-ARG-PRO-NH2 Usage And Synthesis

Uses

Gly-Pro-Arg-Pro amide has been used-

  • as a constituent of buffer during fluid-phase and bound thrombin inhibition assays, to determine the activity of thrombin
  • for blocking fibrin polymerization and preventing fibrin clot formation in presence of α-thrombin, in blood obtained from mice
  • during preparation of human soluble fibrin, to block the polymerization of soluble fibrin

General Description

Gly-Pro-Arg-Pro is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein.

Biochem/physiol Actions

Gly-Pro-Arg-Pro peptide suppresses the early steps of fibrin polymerization. The amide derivative of this peptide prevents the degradation of fibrinogen and fragment D by plasmin, even in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid).

H-GLY-PRO-ARG-PRO-NH2Supplier

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Email
ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Chemsky (shanghai) International Co.,Ltd
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021-50135380
Email
shchemsky@sina.com
Sigma-Aldrich
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021-61415566 800-8193336
Email
orderCN@merckgroup.com
Creative Peptides
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Email
info@creative-peptides.com