N-Acetyl-4-piperidone Chemical Properties

Boiling point:

218 °C(lit.)

Density 

1.146 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.503(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,Room Temperature

form 

Oily Liquid

pka

-0.72±0.20(Predicted)

Specific Gravity

1.16

color 

Clear orange

Water Solubility 

Soluble in water. Insoluble in acetic acid.

BRN 

116031

CAS DataBase Reference

32161-06-1(CAS DataBase Reference)

NIST Chemistry Reference

1-Acetyl-4-piperidone(32161-06-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

23-24/25-36-26

WGK Germany 

3

F 

10

HS Code 

29333990

MSDS

• Language:English Provider:1-Acetyl-4-piperidone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

N-Acetyl-4-piperidone Usage And Synthesis

Chemical Properties

clear orange oily liquid

Uses

1-Acetyl-4-piperidone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs, and manufacture of fentanyl.

Purification Methods

Purify it by fractional distillaton through a short Vigreux column (15mm, p 11). The 2,4-dinitrophenylhydrazone has m 212-213o (from EtOH). It is freely soluble in H2O but insoluble in Et2O. [McElvain & McMahon J Am Chem Soc 71 901 1949, Beilstein 21/6 V 246.]

N-Acetyl-4-piperidone(32161-06-1)Related Product Information

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