H-SER-PHE-LEU-LEU-ARG-ASN-PRO-OH
H-SER-PHE-LEU-LEU-ARG-ASN-PRO-OH Basic information
- Product Name:
- H-SER-PHE-LEU-LEU-ARG-ASN-PRO-OH
- Synonyms:
-
- SFLLRNP
- SER-PHE-LEU-LEU-ARG-ASN-PRO
- THROMBIN RECEPTOR (42-48) AGONIST, HUMAN
- thrombinreceptorpeptidesfllrnp
- Thrombin Receptor (42-48), human
- H-SER-PHE-LEU-LEU-ARG-ASN-PRO-OH
- Thrombin Receptor (1-7), human
- Proteinase Activated Receptor 1 (1-7) (huMan), ThroMbin Receptor (1-7) (huMan), SFLLRNP, ThroMbin Receptor Activator Peptide 7, PAR-1 (1-7) (huMan), Coagulation Factor II Receptor (1-7) (huMan)
- CAS:
- 145229-76-1
- MF:
- C39H63N11O10
- MW:
- 845.99
- Product Categories:
-
- peptide
- proteins
- Mol File:
- 145229-76-1.mol
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H-SER-PHE-LEU-LEU-ARG-ASN-PRO-OH Chemical Properties
- storage temp.
- -15°C
- form
- Solid
- color
- White to off-white
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H-SER-PHE-LEU-LEU-ARG-ASN-PRO-OH Usage And Synthesis
Uses
TRAP-7 is a thrombin receptor (PAR) activating peptide. TRAP-7 stimulates total inositol phosphate (IP) accumulation and phosphorylation of a specific endogenous substrate for activated PKC. TRAP-7 can be used in cardiovascular disease research[1].
References
[1] Webb ML, et al. Effects of thrombin receptor activating peptide on phosphoinositide hydrolysis and protein kinase C activation in cultured rat aortic smooth muscle cells: evidence for "tethered-ligand" activation of smooth muscle cell thrombin receptors. Biochem Pharmacol. 1993 Apr 22;45(8):1577-82. DOI:10.1016/0006-2952(93)90297-a
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