Phenidone Chemical Properties

Melting point:

119-121 °C(lit.)

Boiling point:

288.88°C (rough estimate)

Density 

1.1436 (rough estimate)

vapor pressure 

0.002Pa at 25℃

refractive index 

1.5600 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

methanol: 0.1 g/mL, clear

form 

White to off-white solid.

pka

9.50±0.30(Predicted)

color 

White to Light yellow to Light orange

Water Solubility 

SOLUBLE IN HOT WATER

Merck 

14,7309

BRN 

131856

Stability:

Stable, but light sensitive. Incompatible with strong acids, strong oxidizing agents, strong bases.

LogP

0.119 at 25℃

CAS DataBase Reference

92-43-3(CAS DataBase Reference)

NIST Chemistry Reference

1-Phenyl-3-pyrazolidinone(92-43-3)

EPA Substance Registry System

3-Pyrazolidinone, 1-phenyl- (92-43-3)

Safety Information

Hazard Codes 

Xn,N

Risk Statements 

22-51/53

Safety Statements 

61

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

2

RTECS 

UQ8750000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29331990

Toxicity

LD50 orl-rat: 200 mg/kg KODAK* -,-,71

MSDS

• Language:English Provider:1-Phenyl-3-pyrazolidinone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Phenidone Usage And Synthesis

Chemical Properties

light beige powder or crystals

Uses

Phenidone is used as black and white photographic developer.

Uses

Phenidone inhibits both the LO (lipoxygenase) and Cox (cyclooxygenase) pathways, the synthesis of Fos-related antigen protein, and is described as an anti-inflammatory and anti-oxidant compound. Phenidone has been shown to block neurotoxicity induced by kainate, and weakens oxidative stress induced by lipopolysaccharide.

Flammability and Explosibility

Not classified

Safety Profile

Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.

Phenidone(92-43-3)Related Product Information

• 2-Phenylphenol
• Triphenylmethyl Chloride
• Triphenylphosphine
• 1-Phenyl-2-nitropropene
• Sorafenib
• Phenylhydrazine
• PHENYL VALERATE
• 1-PHENYL-2-PROPANOL
• (FORMYLMETHYLENE)TRIPHENYLPHOSPHORANE
• Oxadixyl
• 1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one
• 4,5-dihydro-a-(hydroxyMethyl)-a,3-diMethyl-5-oxo-1-phenyl-1H-Pyrazole-4-Methanesulfonic acid
• BISPYRAZOLONE
• Edaravone Impurity 26
• 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one
• ethyl 3-acetoxy-2-butenoate
• Ethyl (3E)-3-(2-phenylhydrazin-1-ylidene)butanoate
• 1H-Pyrazole,3-ethoxy-5-methyl-1-phenyl-(9CI)