Octapeptide 2 Chemical Properties

Boiling point:

1566.9±65.0 °C(Predicted)

Density 

1.394±0.06 g/cm3(Predicted)

pka

3.22±0.10(Predicted)

form 

Solid

color 

White to off-white

Sequence

Thr-Ala-Glu-Glu-His-Glu-Val-Met

Octapeptide 2 Usage And Synthesis

Description

Octapeptide 2 is a synthetic peptide with strengthening and hair growth promoting properties. It not only promotes the development and activity of hair follicle stem cells, thus promoting hair growth. It also accelerates cell migration in the hair follicle, inhibits apoptosis, strengthens the hair and gives it a healthy lustre. It also inhibits the production of proteases and restores hair growth. In addition, it stimulates fibroblasts to synthesise collagen, elastin and fibrous connective proteins, strengthening hair toughness.

Uses

Octapeptide-2 is a biomimetic peptide that mimics the thymosin-β4 growth factor. Octapeptide-2 can promote hair growth, reduce cell apoptosis, and increase the proliferation of keratinocytes. Octapeptide-2 can be used in the research of hair loss and alopecia areata[1][2].

References

[1] Rinaldi F, et al. Randomized controlled trial on a PRP-like cosmetic, biomimetic peptides based, for the treatment of alopecia areata. J Dermatolog Treat. 2019;30(6):588-593. DOI:10.1080/09546634.2018.1544405
[2] Lazzari T, et al. Efficacy of Autologous Platelet-Rich Plasma alone or in Combination with a Lotion Containing Growth-Factor like Polypeptides and Taurine in the Treatment of Androgenic Alopecia: A Randomized, Prospective, Assessor-Blinded Trial. J Clin Exp Dermatol Res, 2019, 10: 506.

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