Propargyl-PEG3-amine
Propargyl-PEG3-amine Basic information
- Product Name:
- Propargyl-PEG3-amine
- Synonyms:
-
- Azido-PEG3-propargyl
- Propargyl-PEG3-amine
- Propargyl-PEG3-azide
- HC≡C-CH2-PEG3-NH2
- Propyne-PEG3-amine
- Alkyne-PEG3-NH2
- PROPARGYL-PEG3-NH2
- 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)prop-1-yne
- CAS:
- 932741-18-9
- MF:
- C9H15N3O3
- MW:
- 213.24
- Product Categories:
-
- peg
- Mol File:
- 932741-18-9.mol
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Propargyl-PEG3-amine Usage And Synthesis
Biological Activity
Propargyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Propargyl-PEG3-amineSupplier
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Borenpharm Co., Ltd
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