3'-DEOXYGUANOSINE Chemical Properties

Melting point:

<300℃ (water )

Density 

2.08±0.1 g/cm3 (20 ºC 760 Torr)

storage temp. 

2-8°C(protect from light)

solubility 

DMSO (Slightly), Water (Slightly, Heated, Sonicated)

form 

Solid

color 

White to Off-White

InChI

InChI=1S/C10H13N5O4/c11-10-13-7-6(8(18)14-10)12-3-15(7)9-5(17)1-4(2-16)19-9/h3-5,9,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,9+/m0/s1

InChIKey

OROIAVZITJBGSM-OBXARNEKSA-N

SMILES

OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@H](O)C1

Safety Information

WGK Germany 

3

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

3'-DEOXYGUANOSINE Usage And Synthesis

Description

3''-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors, in order to study structure-activity relationships. This compound can also be used to selectively impair transcription.

Chemical Properties

solid

Uses

3’-Deoxyguanosine is a derivative of guanosine, a ligand which may be complexe with enzymes such as purine nucleoside phosphorylase and receptors. Potential anti-amoebic agent.

Definition

ChEBI: 3'-deoxyguanosine is a 3'-deoxyribonucleoside having guanine as the nucleobase. It has a role as an EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor. It is a 3'-deoxyribonucleoside and a member of guanosines.

References

[1] FERNANDA CANDURI. Structure of human PNP complexed with ligands.[J]. Acta crystallographica. Section D, Biological crystallography, 2005, 61 Pt 7: 856-862. DOI: 10.1107/s0907444905005421
[2] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[3] ROBERT W KING  Matthew W J  Marianne Zecher. Inhibition of the replication of a hepatitis C virus-like RNA template by interferon and 3’-deoxycytidine.[J]. Antiviral Chemistry and Chemotherapy, 2002, 13 6: 363-370. DOI: 10.1177/095632020201300604

3'-DEOXYGUANOSINE(3608-58-0)Related Product Information

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