12(R)-HEPE
12(R)-HEPE Basic information
- Product Name:
- 12(R)-HEPE
- Synonyms:
-
- 12(R)-HEPE
- 12R-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID
- MCRJLMXYVFDXLS-IHWYZUJNSA-N
- 5,8,10,14,17-Eicosapentaenoic acid, 12-hydroxy-, (5Z,8Z,10E,12R,14Z,17Z)-
- 12(R)-hydroxy-5(Z),8(Z),10(E),14(Z),17(Z)-EPA
- CAS:
- 109430-12-8
- MF:
- C20H30O3
- MW:
- 318.45
- Mol File:
- 109430-12-8.mol
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12(R)-HEPE Chemical Properties
- solubility
- 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
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12(R)-HEPE Usage And Synthesis
Description
12(R)-
Uses
12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin, S. purpuratus.1 The biological activity of 12(R)-HEPE has not been extensively documented, but may be similar to that of 12(R)-HETE.
Definition
ChEBI: 12R-HEPE is a HEPE.
References
[1] Masferrer, et al. 12(R)-Hydroxyeicosatetraenoic acid, an endogenous corneal arachidonate metabolite, lowers intraocular pressure in rabbits. Invest. Ophthalmol. Vis. Sci. 31(3), 535-539 (1990).
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