4F-MPH Chemical Properties

Boiling point:

329.4±22.0 °C(Predicted)

Density 

1.130±0.06 g/cm3(Predicted)

pka

9.49±0.10(Predicted)

InChI

InChI=1S/C14H18FNO2/c1-18-14(17)13(12-4-2-3-9-16-12)10-5-7-11(15)8-6-10/h5-8,12-13,16H,2-4,9H2,1H3

InChIKey

XISBAJBPDVRSPG-UHFFFAOYSA-N

SMILES

C(C1NCCCC1)(C1C=CC(F)=CC=1)C(=O)OC

4F-MPH Usage And Synthesis

Uses

4F-MPH is a novel psychoactive substance that is a fluorinated analogue of the prescription central nervous system stimulant methylphenidate (MPH), a dopamine and norepinephrine reuptake inhibitor used to treat attention deficit hyperactivity disorder. (±)-threo- and (±)-erythro- diastereomers (±) are present in 4F-MPH powders, but the bioactive compounds are (±)-threo-4-fluoromethylphenidate (4F-MPH). At present, studies have shown that 4F-MPH is toxic and has certain effects on the mind and heart of the human body^[1].

References

[1] PIETRO PAPA. Analytically Confirmed Intoxication by 4-Fluoromethylphenidate, an Analog of Methylphenidate.[J]. Journal of analytical toxicology, 2019, 43 5: e1-e7. DOI:10.1093/jat/bkz001.

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