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Lincomycin EP Impurity B

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Lincomycin EP Impurity B Basic information

Product Name:
Lincomycin EP Impurity B
Synonyms:
  • Dehydrolincomycin
  • Lincomycin hydrochloride impurity B
  • Lincomycin EP Impurity B
  • Lincomycin Impurity 3(Lincomycin EP Impurity B)
  • (2S)-4'-Depropyl-4'-propylidenelincomycin (Mixture of Diastereomers)
  • D-erythro-α-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[[(2S)-1-methyl-4-propylidene-2-pyrrolidinyl]carbonyl]amino]-1-thio-
  • (2S)-4'-Depropyl-4'-propylidenelincomycin
  • Methyl 6,8-dideoxy-6-[[[(2S,4EZ)-1-methyl-4-propylidenepyrrolidin-2-yl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside (propylidene analogues)
CAS:
37744-65-3
MF:
C18H32N2O6S
MW:
404.52
Mol File:
37744-65-3.mol
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Lincomycin EP Impurity B Chemical Properties

Melting point:
89-94°C
Boiling point:
665.5±55.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
12.91±0.70(Predicted)
color 
White to Off-White
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Lincomycin EP Impurity B Usage And Synthesis

Uses

(2S)-4''-Depropyl-4''-propylidenelincomycin is an impurity of Lincomycin (L466200), an antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial.

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