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Atorvastatin Acetonide tert-Butyl Ester

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Atorvastatin Acetonide tert-Butyl Ester Basic information

Product Name:
Atorvastatin Acetonide tert-Butyl Ester
Synonyms:
  • (4R-CIS)-1,1-DIMETHYLETHYL-6-[2-[2-(4-FLUOROPHENYL)-5-(1-ISOPROPYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROL-1-YL]ETHYL]-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • (4R-CIS)-[1,1-DIMETHYLETHYL-6-[(2-FLUOROPHENYL)-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO) CARBONYL]-1H-PYRROL-1-YL]ETHYL]-2, 2-DIMETHYL-1, 3-DIOXANE-4-ACETATE
  • (4R-CIS)-6-[2-[2-(4-FLUOROPHENYL)-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROL-1-YL]ETHYL]-2,2-DIMETHYL-1,3-DIOXANE-4-ACETIC ACID, 1,1-DIMETHYLETHYL ESTER
  • L-1(4R-Cis)-1,1-DiMethylethyl-6- 2- 2-(4-Fluorophenyl)-5-(1-Isopropyl)-3-Phenyl-4 (PhenylaMino)carbonyl -1H-pyrrol-1-yl Ethyl -2,2-DiMethyl-1,3-Dioxane-4-Acetate
  • tert-butyl (4r,6r)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate
  • tert-Butyl (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1-pyrrolyl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate
  • tert-Butyl 2-[(4R,6R)-6-[2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]
  • (4R-cis)-1,1-dimethylethyl-6-[2-[2-(4-fluorophenyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:
125971-95-1
MF:
C40H47FN2O5
MW:
654.81
EINECS:
700-258-0
Product Categories:
  • INTERMEDIATES OF ATORVASTATIN
  • Intermediates & Fine Chemicals. Pfizer compounds
  • (intermediate of atorvastatin)
  • Chiral Reagents
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Complex Molecules
Mol File:
125971-95-1.mol
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Atorvastatin Acetonide tert-Butyl Ester Chemical Properties

Melting point:
144-148 °C(lit.)
alpha 
6.5 º (c=1, chloroform)
Boiling point:
678.0±55.0 °C(Predicted)
Density 
1.14±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
13.57±0.70(Predicted)
form 
Solid
color 
White
optical activity
[α]20/D +6.5°, c = 1 in chloroform
InChIKey
NPPZOMYSGNZDKY-ROJLCIKYSA-N
CAS DataBase Reference
125971-95-1(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3
HS Code 
29349990
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Atorvastatin Acetonide tert-Butyl Ester Usage And Synthesis

Chemical Properties

White Solid

Uses

Atorvastatin Acetonide tert-Butyl Ester (Atorvastatin EP Impurity I) is an Atorvastatin intermediate.

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