(S)-(-)-1-(1-Naphthyl)ethylamine Chemical Properties

Boiling point:

153 °C/11 mmHg (lit.)

alpha 

-60 º (C=2, MEOH)

Density 

1.067 g/mL at 20 °C (lit.)

refractive index 

n20/D 1.623(lit.)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Soluble in chloroform, ethanol.

form 

Liquid

pka

9.26±0.40(Predicted)

color 

brown

optical activity

[α]20/D 59°, c = 5 in methanol

Sensitive 

Air Sensitive

BRN 

2208024

InChIKey

RTCUCQWIICFPOD-VIFPVBQESA-N

CAS DataBase Reference

10420-89-0(CAS DataBase Reference)

NIST Chemistry Reference

(S)-(-)-«alpha»-(1-naphthyl)ethylamine(10420-89-0)

EPA Substance Registry System

1-Naphthalenemethanamine, .alpha.-methyl-, (.alpha.S)- (10420-89-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

RIDADR 

2735

WGK Germany 

3

RTECS 

QJ6963000

F 

10-34

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29214990

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

(S)-(-)-1-(1-Naphthyl)ethylamine Usage And Synthesis

Description

(S)-(-)-1-(1-Naphthyl)ethylamine is an organic compound used as a raw material for organic synthesis. Chiral moieties were connected to the heteroatom-bridged calix-triazin scaffold by reactions of (S)- or (R)-(+)-1-(1-Naphthyl)ethylamine with tetraazacalix[4]arene[2]triazine.

Chemical Properties

(S)-(-)-1-(1-Naphthyl)ethylamine Appearance is colourless to light orange to yellow transparent liquid, hygroscopicity, thermal sensitivity. Density: 1.067 g/mL (lit.) at 20 °C; Boiling Point: 125 °C/3 mmHg; Specific Gravity (20/20): 1.07; Refractive Index: 1.62. Store under inert gas.

Uses

(S)-(-)-1-(1-Naphthyl)ethylamine is used in the asymmetric synthesis of α-cyanocarboxylates. Also used in the synthesis of chiral imadazolin-2-ylidene ligands used in organometallic catalysis. Chiral/Asymmetric synthesis.

Uses

Employed in a preparation of a chiral thiourea solvating agent useful for enantiodiscrimination of α-hydroxy and α-amino acids by ¹H NMR.

Purification Methods

Purify the amine by distillation in a good vacuum. [Mori et al. Tetrahedron 37 1343 1981, cf Wilson in Topics Stereochem (Allinger and Eliel eds) v o l 6 135 1971, Fredga et al. Acta Chem Scand 11 1609 1957.] The hydrochlorides crystallise from H2O [] D 18 ±3.9o (c 3, H2O), and the sulfates recrystallise from H2O as tetrahydrates m 230-232o. The RS-amine has b 153o/11mm, 156o/15mm, 183.5o/41mm [Blicke & Maxwell J Am Chem Soc 6 1 1780 1939]. [Beilstein 12 III 3111.]

(S)-(-)-1-(1-Naphthyl)ethylamine(10420-89-0)Related Product Information

• Ethylamine
• L-1-Phenylethylamine
• Triethylamine hydrochloride
• Ethambutol
• Etamsylate
• 1-(1-NAPHTHYL)-2-THIOUREA
• Diethylstilbestrol
• Diethylamine
• Triethylamine
• (1R,2R)-(-)-1,2-Diaminocyclohexane
• (1S,2R)-2-Amino-1,2-diphenylethanol
• (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride
• N-benzyl-1-(1-naphthyl)ethylamine hydrochloride,(R)-(-)-N-BENZYL-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE,(R)-N-BENZYL 1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE
• 4-(TRIFLUOROMETHYL)HYDROCINNAMIC ACID
• 1-NAPHTHALEN-2-YL-ETHYLAMINE
• 3-(Trifluoromethyl)benzaldehyde
• Methanesulfonic acid 3-(3-trifluoroMethylphenyl)propyl ester
• 1-(7,8-dihydronaphthalen-1-yl)ethan-1-amine hydrochloride