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3,4'-Dichloropropiophenone

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3,4'-Dichloropropiophenone Basic information

Product Name:
3,4'-Dichloropropiophenone
Synonyms:
  • (2-CHLOROETHYL)-4-CHLOROPHENYLKETONE
  • 3,4'-DICHLOROPROPIONPHENONE
  • 3',4-DICHLOROPROPIOPHENONE
  • 3,4'-DICHLOROPROPIOPHENONE
  • BETA,4-DICHLOROPROPIOPHENONE
  • CHEMPACIFIC 42352
  • 3,4-Dichloropropiophenone95%
  • 4-Dichloropropiophenone, 96%
CAS:
3946-29-0
MF:
C9H8Cl2O
MW:
203.07
EINECS:
223-537-4
Product Categories:
  • Acetophenone Series
  • C9
  • Carbonyl Compounds
  • Ketones
Mol File:
3946-29-0.mol
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3,4'-Dichloropropiophenone Chemical Properties

Melting point:
48-51 °C(lit.)
Boiling point:
135-137 °C0.6 mm Hg(lit.)
Density 
1.2568 (rough estimate)
refractive index 
1.5500 (estimate)
Flash point:
178 °F
storage temp. 
Refrigerator
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Solid
color 
White to Pale Yellow
BRN 
1866915
CAS DataBase Reference
3946-29-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C,Xi
Risk Statements 
34-36/37-36/37/38
Safety Statements 
23-26-27-36/37/39-45-37/39
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
HazardClass 
8
PackingGroup 
III
HS Code 
2914790090

MSDS

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3,4'-Dichloropropiophenone Usage And Synthesis

Chemical Properties

yellow to brown crystals or crystalline powder

Uses

3’,4’-Dichloropropiophenone is used as a reagent in the preparation of antidepressant aryl-alkyl-piperidine derivatives. Also used in the synthesis of mGlu5 receptor negative allosteric modulators. Also in the genetic screening of compounds countering the growth of methylthioadenosine phosphorylase involved in cancer spread.

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