1,2,3-Trimethoxybenzene Chemical Properties

Melting point:

43-47 °C (lit.)

Boiling point:

241 °C (lit.)

Density 

1.112 g/mL at 25 °C (lit.)

refractive index 

1.5470 (estimate)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), DMSO (Slightly)

form 

Powder

color 

White to dark beige

Water Solubility 

Insoluble in water.

BRN 

1910422

LogP

1.530

CAS DataBase Reference

634-36-6(CAS DataBase Reference)

NIST Chemistry Reference

1,2,3-Trimethoxybenzene(634-36-6)

EPA Substance Registry System

Benzene, 1,2,3-trimethoxy- (634-36-6)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

22-24/25

WGK Germany 

3

TSCA 

Yes

HS Code 

29093090

MSDS

• Language:English Provider:1,2,3-Trimethoxybenzene
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1,2,3-Trimethoxybenzene Usage And Synthesis

Chemical Properties

WHITE TO DARK BEIGE POWDER

Uses

1,2,3-Trimethoxybenzene can be used for RSM-optimised slow pyrolysis of rice husk for bio-oil production.

Uses

1,2,3-Trimethoxybenzene was used to study the effect of solvent on photoinduced electron-transfer reactions.

Definition

ChEBI: A methoxybenzene that is benzene substituted by methoxy groups at positions 1, 2 and 3 respectively.

General Description

1,2,3-Trimethoxybenzene on condensation with 2,4-diamino-5-(hydroxymethyl)pyrimidine yields 2,4-diamino-5-(2,3,4-trimethoxybenzyl)pyrimidine.

Synthesis

Aqueous sodium hydroxide (40%，150 ml) is added dropwise during3-4 hr to a stirred mixture of pyrogallol (42 g，0.33 mole)，sodiumhydrosulphite (10 g,0.057 mole)，dimethyl sulphate (146 ml，194.60 g,1.54 mole) kept at 18-22°. Ice (1 kg) is then added and the reactionmixture left overnight. The separated solid is filtered and washed withwater. It is crystallised from methanol as colourless prisms. Yield 37.5 g(66.9%). M.p. 46-47°.Some more product (4 g, 7.1 %) is obtained byextraction of the mother liquor with ether (lit. m.p.46-47°).

Purification Methods

Sublime it under vacuum. [Beilstein 6 H 1081, 6 I 540, 6 II 1066, 6 III 6265, 6 IV 7329.]

1,2,3-Trimethoxybenzene(634-36-6)Related Product Information

• 4-Methoxyphenylacetic acid
• m-Anisyl alcohol
• 3-(METHOXYMETHOXY)BENZALDEHYDE
• p-Anisaldehyde
• (Trifluoromethoxy)benzene
• (3-Methoxyphenyl)acetonitrile
• Trimethyl phosphite
• Benzene
• o-Anisaldehyde
• Anisole
• Colchicine
• 3,4,5-Trimethoxybenzoyl chloride
• 2,3,4-Trimethoxybenzaldehyde
• 3,4,5-TRIMETHOXYCINNAMIC ACID
• 3,4,5-Trimethoxybenzonitrile
• 1,3,5-TRIMETHOXYBENZENE pure,sym-Trimethoxybenzene
• 3,4,5-Trimethoxy benzoic acid
• 1,4,5-Trimethoxybenzene,1,2,4-TRIMETHOXYBENZENE