N-Carbethoxy-4-piperidone Chemical Properties

Boiling point:

95-98 °C (1 mmHg)

Density 

1.135 g/mL at 25 °C (lit.)

vapor pressure 

0.2-0.37Pa at 20-25℃

refractive index 

n20/D 1.475(lit.)

Flash point:

190 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Liquid

pka

-1.59±0.20(Predicted)

color 

Clear colorless to pale yellow

PH

4.6 (H2O, 20℃)(saturated solution)

Water Solubility 

slightly soluble

BRN 

640967

InChIKey

LUBGFMZTGFXIIN-UHFFFAOYSA-N

LogP

0 at 20℃ and pH6.5-6.7

CAS DataBase Reference

29976-53-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

36/38-22-36/37/38-20/21/22

Safety Statements 

23-24/25-37/39-26-36

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29333999

MSDS

• Language:English Provider:N-Carbethoxy-4-piperidone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

N-Carbethoxy-4-piperidone Usage And Synthesis

Chemical Properties

clear colorless to pale yellow colored liquid

Uses

Ethyl 4-oxo-1-piperidinecarboxylate (1-carbethoxy-4-piperidone) was used to prepare tertiary alcohols.

Uses

N-Carbethoxy-4-piperidone (Loratadine EP Impurity H) is used in the preparation of 3-hydrazinopyridazines as antihypertensive agents as well as γ-carboline derivatives as potential serotonergic agents. It is also an impurity of Loratadine (L469575).

N-Carbethoxy-4-piperidone (29976-53-2)Related Product Information

• Ethylparaben
• RESMETHRIN
• Ethyl acrylate
• 4-Piperidinone
• Ethyl acetate
• N-Carbobenzyloxyglycine
• Ethylbenzene
• Haloperidol
• Ethyl cellulose
• Ethanol
• tert-Butyl cyanoacetate
• 11,11'-(PIPERAZINE-1,4-DIYL)-BIS-8-CHLORO-5H-DIBENZE[B,E][1,4]-DIAZEPINE
• 1-Acetyl-2-imidazolidinone
• N-(tert-Butoxycarbonyl)-4-piperidone
• 1-FMOC-4-PIPERIDONE
• 1-Cbz-4-Piperidone
• Diethyl ether
• N-Boc-Nortropinone