2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoate CAS#: 1027371-75-0

2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoate Basic information

Product Name:

2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoate

Synonyms:

m-PEG1-NHS ester
3-Methoxy-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester
2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoate
Propanoic acid, 3-methoxy-, 2,5-dioxo-1-pyrrolidinyl ester
MeO-NHS
3-Methoxy-propanoic acid 2,5-dioxo-1-pyrrolidinyl ester

CAS:

1027371-75-0

MF:

C8H11NO5

MW:

201.18

Mol File:

1027371-75-0.mol

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2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoate Chemical Properties

Boiling point:: 292.8±42.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: Storage temp. -20°C
solubility: Soluble in DCM
form: Solid
color: White to light yellow

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2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoate Usage And Synthesis

Description

m-PEG1-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG1-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

IC 50

PEGs; Alkyl/ether

References

[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74

2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoateSupplier

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