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4,6-Dibromo-pyrazolo[1,5-a]pyridine-3-carbonitrile

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4,6-Dibromo-pyrazolo[1,5-a]pyridine-3-carbonitrile Basic information

Product Name:
4,6-Dibromo-pyrazolo[1,5-a]pyridine-3-carbonitrile
Synonyms:
  • 4,6-Dibromo-pyrazolo[1,5-a]pyridine-3-carbonitrile
  • Pyrazolo[1,5-a]pyridine-3-carbonitrile, 4,6-dibromo-
CAS:
2068065-63-2
MF:
C8H3Br2N3
MW:
300.94
EINECS:
200-795-6
Mol File:
2068065-63-2.mol
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4,6-Dibromo-pyrazolo[1,5-a]pyridine-3-carbonitrile Chemical Properties

Density 
2.12±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
-2.88±0.30(Predicted)
InChI
InChI=1S/C8H3Br2N3/c9-6-1-7(10)8-5(2-11)3-12-13(8)4-6/h1,3-4H
InChIKey
FBKJJSFJKWOLQA-UHFFFAOYSA-N
SMILES
C12=C(C#N)C=NN1C=C(Br)C=C2Br
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4,6-Dibromo-pyrazolo[1,5-a]pyridine-3-carbonitrile Usage And Synthesis

Uses

4,6-Dibromo-pyrazolo[1,5-a]pyridine-3-carbonitrile is used as a reagent for organic synthesis or as a pharmaceutical intermediate component. It can be used to prepare Selpercatinib, an oral selective inhibitor of tyrosine kinase receptors for the treatment of advanced RET mutant medullary thyroid carcinoma (MTC) and advanced RET fusion-positive non-small cell lung cancer (NSCLC).

4,6-Dibromo-pyrazolo[1,5-a]pyridine-3-carbonitrileSupplier

Shanghai Huiyu Biological Technology Co., LTD Gold
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17280940401
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PharmaBlock Sciences (Nanjing), Inc. Gold
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4000255188 13327728092
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Tetranov Biopharm
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13526569071
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sales@leadmedpharm.com
Shanghai YuanQi Biotechnology Co., Ltd.
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+86-2332782371 +86-18120098618
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sales@adobechem.com
Xiamen Yunfan Biotech Co., Ltd.
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0592-7828678 18050056030
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357187337@qq.com
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