SUFENTANIL CITRATE CAS#: 60561-17-3

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SUFENTANIL CITRATE

Basic information Safety Supplier Related

SUFENTANIL CITRATE Basic information

Product Name:

SUFENTANIL CITRATE

Synonyms:

SUFENTANIL CITRATE
n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-n-phenylpropionam
n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)-propionanilidcitr
n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilidecitrat
r30730citratesalt
r33800
sufentanylcitrate
N-[4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamide citrate

CAS:

60561-17-3

MF:

C28H38N2O9S

MW:

578.68

EINECS:

262-295-4

Product Categories:

Aromatics
Heterocycles
Organics
Intermediates & Fine Chemicals
Pharmaceuticals

Mol File:

60561-17-3.mol

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SUFENTANIL CITRATE Chemical Properties

Melting point:: 96.60C
Flash point:: 9℃
storage temp.: -20°C Freezer
solubility: H2O: soluble1mg/mL, clear
form: powder
color: white to beige
Stability:: Hygroscopic

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Safety Information

Hazard Codes: T+,T,F
Risk Statements: 26/27/28-39/23/24/25-23/24/25-11
Safety Statements: 26-27-28-36/37/39-45-36/37-16-7
RIDADR: 3249
WGK Germany: 3
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 2934910000
Toxicity: LD50 intravenous in dog: 14100ug/kg

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SUFENTANIL CITRATE Usage And Synthesis

Chemical Properties

Crystalline Solid

Uses

Potent derivative of Fentanyl. Analgesic (narcotic). Controlled substance (opiate)

Definition

ChEBI: Sufentanil citrate is an anilide.

brand name

Sufenta (Akorn).

General Description

Sufentanil is a short acting synthetic opioid analgesic most commonly used for pain relief during medical operations. This certified solution standard is applicable to use in clinical toxicology, pain prescription monitoring, or forensic analysis by LC-MS/MS or GC/MS. Sufentanil is sold under the trade name Sufenta.

Clinical Use

Addition of the 4-methoxymethyl group and bioisosteric replacement of the phenyl with a 2-thiophenyl on the fentanyl structure results in a 10-fold increase in μ opioid activity. The resultant compound, sufentanil, is 600 to 800 times more potent than morphine. Despite its greater sedative and analgesic potency, sufentanil produces less respiratory depression at effective anesthetic doses. Sufentanil is available in an intravenous dosage form, and it is used for anesthetic procedures. It has a faster onset and shorter duration of action than fentanyl. The short duration is caused by redistribution from brain tissues after intravenous dosage.

Veterinary Drugs and Treatments

An opioid analgesic, sufentanil may be useful as an anesthesia adjunct or as an epidural analgesic. In humans, it has been used as the primary anesthetic in intubated patients with assisted ventilation, and as a post-operative analgesic.

SUFENTANIL CITRATESupplier

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