BPV(HOPIC)
BPV(HOPIC) Basic information
- Product Name:
- BPV(HOPIC)
- Synonyms:
-
- BPV(HOPIC)
- DIPOTASSIUM BISPEROXO(5-HYDROXYPYRIDINE-2-CARBOXYL)OXOVANADATE (V)
- Bisperoxovanadium(HOpic)
- K2[VO(O2)2C6H4NO3]
- bpV(HOpic) (potassium salt)
- bpV(HOpic) (potassium salt, technical grade)
- MAPK/ERK,Phosphatase and tensin homolog,Inhibitor,PTEN,MMAC1,inhibit,PI3K/AKT,BpV(HOpic),signalling
- CAS:
- 722494-26-0
- MF:
- C6H4K2NO8V
- MW:
- 347.24
- Mol File:
- Mol File
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BPV(HOPIC) Chemical Properties
- storage temp.
- -20°C
- solubility
- H2O: soluble20mg/mL, clear
- form
- powder
- color
- faint yellow to dark yellow
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BPV(HOPIC) Usage And Synthesis
Uses
bpV(HOpic) has been used in pharmacological perturbation of cell migration related signaling pathway.
Biochem/physiol Actions
bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN compared to 4.9 μM for PTPβ and 25.3 μM for PTP-1β. bpV(HOpic) has been shown to enhance PI3K/Akt signaling that could prevent myocardium from ischemia-reperfusion injury.
BPV(HOPIC)Supplier
Guangzhou Isun Pharmaceutical Co., Ltd
- Tel
- 020-39119399 18927568969
- isunpharm@qq.com
Sigma-Aldrich
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- 021-61415566 800-8193336
- orderCN@merckgroup.com
BOC Sciences
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- 16314854226
- info@bocsci.com
Shanghai EFE Biological Technology Co., Ltd.
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- 021-65675885 18964387627
- info@efebio.com
Beijing OKA biological technology co., LTD
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- 010-010-62971590 18548936886
- 3462612863@qq.com