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2,6-Dimethylpyrazine

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2,6-Dimethylpyrazine Basic information

Product Name:
2,6-Dimethylpyrazine
Synonyms:
  • 2,6-dimethyl-pyrazin
  • 2,6-dimethylpyrazine,balance2,5-isomer
  • 3,5-Dimethylpyrazine
  • FEMA NUMBER 3273
  • FEMA 3273
  • 2,6-DIMETHYLPYRAZINE
  • 2,6-DIMETHYL PARADIAZINE
  • 2,6-DIMETHYL-1,4-DIAZINE
CAS:
108-50-9
MF:
C6H8N2
MW:
108.14
EINECS:
203-589-4
Product Categories:
  • Building Blocks
  • Heterocyclic Building Blocks
  • Mono- & Polyalkylpyrazines
  • Alphabetical Listings
  • C-D
  • Flavors and Fragrances
  • Pharmaceutical Raw Materials
  • Pyrazine
  • Heterocyclic Compounds
  • Pyrazines
  • pyrazine Flavor
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
Mol File:
108-50-9.mol
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2,6-Dimethylpyrazine Chemical Properties

Melting point:
35-40 °C(lit.)
Boiling point:
154 °C(lit.)
Density 
0.965(50.0000℃)
FEMA 
3273 | 2,6-DIMETHYLPYRAZINE
refractive index 
1.5000
Flash point:
127 °F
storage temp. 
-20°C
solubility 
Chloroform, Methanol (Slightly)
pka
2.49±0.10(Predicted)
form 
Low Melting Crystalline Solid
color 
Pale yellow
PH
7 (H2O, 20℃)
Odor
at 10.00 % in dipropylene glycol. ethereal cocoa nutty roasted roasted meaty beefy brown coffee buttermilk
Odor Type
chocolate
Water Solubility 
Soluble in water.
JECFA Number
767
BRN 
1726
Dielectric constant
2.6499999999999999
LogP
0.64
CAS DataBase Reference
108-50-9(CAS DataBase Reference)
NIST Chemistry Reference
Pyrazine, 2,6-dimethyl-(108-50-9)
EPA Substance Registry System
Pyrazine, 2,6-dimethyl- (108-50-9)
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Safety Information

Hazard Codes 
Xn,F
Risk Statements 
10-22-37/38-41-11
Safety Statements 
16-26-39
RIDADR 
UN 1325 4.1/PG 2
WGK Germany 
3
RTECS 
UQ2975000
TSCA 
Yes
HazardClass 
4.1
PackingGroup 
III
HS Code 
29339990

MSDS

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2,6-Dimethylpyrazine Usage And Synthesis

Description

2,6-Dimethylpyrazine is one of alkylpyrazines. It occurs naturally in cocoa products, coffee, dairy products, meat, peanuts, pecans, filberts, potato products, rum and whisky, soy products. It is used as a flavoring agent in foods such as cereals and products such as cigarettes.

Reference

Glovanni Fenaroli, Fenaroli's Handbook of Flavor Ingredients, 1975, ISBN 0-87819-533-5

Chemical Properties

PALE YELLOW LOW MELTING CRYSTALLINE SOLID

Chemical Properties

2,6-Dimethylpyrazine has a nutty, coffee-like odor.

Occurrence

Reported found in cocoa products, coffee, diary products, peanuts, pecans, filberts, potato products, rum, whiskey, soy products, tomato puree, baked potato, cooked beef and chicken, mushroom, roasted barley, roasted pecan, tea, and Virginia tobacco; reported found in grilled beef; also a volatile flavor component of potato chips. Also reported found in cheeses, tamarind, coriander seed and corn tortilla

Uses

2,6-Dimethylpyrazine is used Preparation of chocolate, coffee, meat and nuts and other flavors

Definition

ChEBI: 2,6-Dimethylpyrazine is a member of pyrazines.

Preparation

By condensation of 1,2-diaminopropane, followed by column chromatography to separate the 2,6-methylpyrazine from the 2,5-dimethylpyrazine.

Aroma threshold values

Detection: 400 to 1500 ppb. Aroma characteristics at 1.0%: musty, cocoa powdery, tobacco, dry leaf tea, earthy mushroom cap and potato-like, meaty, roasted peanut shell, and coffee.

Taste threshold values

Taste characteristics at 5.0 ppm: musty and earthy, nutty peanut shell, cocoa powdery, earthy coffee, yeasty, woody, milk roasted peanut.

2,6-Dimethylpyrazine Preparation Products And Raw materials

Preparation Products

Raw materials

2,6-DimethylpyrazineSupplier

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