Methyl 2-oxindole-4-carboxylate CAS#: 90924-46-2

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Methyl 2-oxindole-4-carboxylate

Basic information Safety Supplier Related

Methyl 2-oxindole-4-carboxylate Basic information

Product Name:

Methyl 2-oxindole-4-carboxylate

Synonyms:

methyl 2-oxo-2,3-dihydro-1H-indole-4-carboxylate
4-Methoxycarbonyl-2-oxindole
Methyl 2-oxindole-4-carbo...
1H-Indole-4-carboxylic acid, 2,3-dihydro-2-oxo-, Methyl ester
METHYL OXINDOLE-4-CARBOXYLATE
METHYL 2-OXINDOLE-4-CARBOXYLATE
Methyl 2-oxoindoline-4-carboxylate
Methyl-2-Dxoindline-4-carboxylate

CAS:

90924-46-2

MF:

C10H9NO3

MW:

191.18

EINECS:

2017-001-1

Product Categories:

Indole/indoline/oxindole
Indole and Indoline
Indole
Indoles

Mol File:

90924-46-2.mol

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Methyl 2-oxindole-4-carboxylate Chemical Properties

storage temp.: Store at 0-8 °C
Appearance: yellow solid

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Safety Information

HS Code: 2933998090

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Methyl 2-oxindole-4-carboxylate Usage And Synthesis

Synthesis

93534-73-7

90924-46-2

General method: Compound 22 (15.8 mmol) or Compound 23 (15.8 mmol) was dissolved in methanol, 10 μl of 10% Pd-C catalyst was added and hydrogen was passed through. The reaction mixture was stirred for 5 hours. After completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated. The residue obtained was purified by recrystallization from methanol to give methyl 4-carboxylate dihydroindol-2-one.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 20, p. 4557 - 4561

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