6-METHYLMERCAPTOPURINE RIBOSIDE Chemical Properties

Melting point:

166°C

Density 

1.4113 (rough estimate)

refractive index 

1.6270 (estimate)

storage temp. 

-20°C

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)

form 

Solid

color 

White to Off-White

Stability:

Incompatible with strong oxidizing agents.

EPA Substance Registry System

6-Methylmercaptopurine riboside (342-69-8)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

UO8985000

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

6-METHYLMERCAPTOPURINE RIBOSIDE Usage And Synthesis

Chemical Properties

white powder

Uses

6-Methylmercaptopurine Riboside (cas# 342-69-8) is a compound useful in organic synthesis.

Uses

6-Methylmercaptopurine riboside (6MMPr) is used in studies on thiopurine metabolism by enzymes such as inosine-5′-monophosphate dehydrogenase and thiopurine methyltransferase. 6MMPr may also be used to study mechanisms of bovine viral diarrhea virus (BVDV) inhibition.

Definition

ChEBI: A thiopurine that is inosine in which the aromatic hydroxy group is replaced by a methylsulfanediyl group.

General Description

White powder.

Air & Water Reactions

Slightly soluble in water.

Biochem/physiol Actions

6-Methylmercaptopurine riboside (6MMPR) is a modified thiopurine nucleoside involved in the inhibition of purine synthesis. It exhibits anti-viral effects against various viruses. 6MMPR is an analog of purine and an inhibitor of nerve growth factor-activated protein kinase N.

Safety Profile

Poison by intraperitoneal route. Experimental teratogenic effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of SO, and NOx.

6-METHYLMERCAPTOPURINE RIBOSIDE(342-69-8)Related Product Information

• 2-AMINO-9-(2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL)-6-THIOPURINE
• 6-(Methylthio)purine
• 2-AMINO-6-HYDROXY-8-MERCAPTOPURINE
• 6-Thioguanosine hydrate
• 2-MERCAPTOPURINE
• 6-METHYL-D3-MERCAPTOPURINE
• 6-Methylthioguanine
• 2,6-Dithiopurine
• 1H-Imidazole-4-carboxylic acid
• 6-thioinosine 5'-monophosphate
• 6-thioinosine 2',3',5'-triacetate
• 6-THIOXANTHINE
• 6-MERCAPTOPURINE RIBOSIDE
• 6-Thioguanine
• 6-ETHYLMERCAPTOPURINE
• 3-sulfanylidene-2,4,9-triazabicyclo[4.3.0]nona-7,10-dien-5-one
• 6-THIO-2'-DEOXYGUANOSINE
• 2',3'-O-ISOPROPYLIDENE-6-THIOINOSINE