Diglycolic anhydride Chemical Properties

Melting point:

92-93 °C (lit.)

Boiling point:

240-241 °C (lit.)

Density 

1.4230

refractive index 

1.5800 (estimate)

Flash point:

240-241°C

storage temp. 

Store below +30°C.

solubility 

Soluble in chloroform.

form 

Crystalline Powder, Crystals or Needles

color 

White to pale cream

Sensitive 

Moisture Sensitive

BRN 

112527

Stability:

Hygroscopic, Moisture Sensitive

InChIKey

PIYNUZCGMLCXKJ-UHFFFAOYSA-N

CAS DataBase Reference

4480-83-5(CAS DataBase Reference)

NIST Chemistry Reference

1,4-Dioxane-2,6-dione(4480-83-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-24/25

RIDADR 

2923

WGK Germany 

3

F 

10-21

HazardClass 

8

PackingGroup 

III

HS Code 

29189090

MSDS

• Language:English Provider:Diglycolic anhydride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Diglycolic anhydride Usage And Synthesis

Chemical Properties

white to off-white

Uses

Diglycolic anhydride is used in the preparation of N,N-diethyldiglycollamsaeure by reacting with diethylamine. It is an useful bio chemical for proteomics research.

Synthesis

50.01 g of diglycolic acid was dissolved in 140 mL of acetic anhydride, Heated to 145 ℃, Add 5 drops of phosphoric acid as initiator, And the mixture was refluxed for 2 hours. After the reaction was stopped, Most acetic anhydride was removed by rotary evaporation at 80 ℃. Approximately 100 mL of liquid was obtained,300 mL of toluene was added. Stirring, and allowed to stand for 10 hours. Vacuum filtration to give 38.89g colourless to white Diglycolic anhydride crystals. The yield was 90%.

Diglycolic anhydride(4480-83-5)Related Product Information

• Isatoic Anhydride
• Trifluoromethanesulfonic anhydride
• Diglycolic acid
• Glutaric anhydride
• Diethylene glycol
• Succinic anhydride
• 1,4-Dioxane
• 2-(2-Aminoethoxy)ethanol
• Diglyme
• Phthalic anhydride
• 2-(2-Chloroethoxy)ethanol
• CIS-BUTENEDIOIC ANHYDRIDE
• Selenium dioxide
• Cyclohexanone
• Buspirone
• Diethylene glycol monobutyl ether
• Methyl methoxyacetate
• Ethyl glycolate