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8-Anilino-1-naphthalenesulfonic acid ammonium salt

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8-Anilino-1-naphthalenesulfonic acid ammonium salt Basic information

Product Name:
8-Anilino-1-naphthalenesulfonic acid ammonium salt
Synonyms:
  • AMMONIUM 8-ANILINO-1-NAPHTHALENESULFONATE
  • ANS-NH4
  • ANS-NH4+
  • ANSA AMMONIUM SALT
  • 8-ANILINONAPHTHALENE-1-SULFONIC ACID AMMONIUM SALT
  • 8-ANILINO-1-NAPHTHALENESULFONIC ACID AMMONIUM SALT
  • 8-ANILINO-1-NAPHTHALENESULFONIC ACID AMMONIUM SALT HYDRATE
  • 1-Naphthalenesulfonicacid,8-(phenylamino)-,monoammoniumsalt
CAS:
28836-03-5
MF:
C16H16N2O3S
MW:
316.38
EINECS:
249-265-6
Product Categories:
  • Intermediates of Dyes and Pigments
Mol File:
28836-03-5.mol
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8-Anilino-1-naphthalenesulfonic acid ammonium salt Chemical Properties

Melting point:
242-244 °C(lit.)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
NaOH: soluble1 N
form 
crystalline
color 
dark green
Water Solubility 
Soluble in water, 1N NaOH, and methanol.
Sensitive 
Light & Air Sensitive & Hygroscopic
λmax
375nm(lit.)
BRN 
3581235
InChI
InChI=1S/C16H13NO3S.H3N/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13;/h1-11,17H,(H,18,19,20);1H3
InChIKey
SYNRZVIFUGIQFF-UHFFFAOYSA-N
SMILES
S(C1=CC=CC2=CC=CC(NC3C=CC=CC=3)=C12)(O)(=O)=O.N
CAS DataBase Reference
28836-03-5(CAS DataBase Reference)
EPA Substance Registry System
1-Naphthalenesulfonic acid, 8-(phenylamino)-, monoammonium salt (28836-03-5)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
3-8-10-23
TSCA 
Yes
HS Code 
29214980

MSDS

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8-Anilino-1-naphthalenesulfonic acid ammonium salt Usage And Synthesis

Chemical Properties

8-Anilinonaphthalene-1-sulfonic acid ammonium salt is a light yellow to yellow-green solid. It is primarily utilized as a dye intermediate in the production of weak acid dark blue 5R and weak acid black BR.

Uses

8-Anilino-1-naphthalenesulfonic Acid Ammonium Salt is a fluorescent probe for protein studies. It is used as sensitive indicator of protein folding, conformational changes and for protein studies. It can also be used in engineering or chemical process of broad-spectrum tunable photoluminescent nanomaterials constructed from modular light-harvesting platform based on macrocyclic amphiphiles.

Application

ANS forms an inclusion complex with cyclodextrin. Such model systems are useful to mimic biological recognition and can be studied by measuring the change in fluorescence of free-ANS to complexed-ANS. When ANS enters the hydrophobic core of cyclodestrin, it′s fluorescence increases . Utilized in the reagent phase of a sodium-selective fiber-optic sensor. The reagent phase also contains a copper(II) polyelectrolyte, which binds to ANSA in the absence of sodium and quenches the fluorescence. In the presence of sodium, ANSA forms a cationic complex creating ion-pairs, causing it to fluoresce . ANS is often incorporated into di-block polymers and can be released by changes in the local environment (i.e., temperature, pH, etc.) . ANS is commonly used as a fluorescence probe to investigate molecular assemblies of surfactants and amphiphilic polymers because a blue shift of the emission maximum indicates the fluorophore is located in less polar media . Fluorescent probe for protein studies using methodologies such as steady-state and dynamic fluorescence measurements.

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