3-Bromoadamantane-1-carboxylic acid Chemical Properties

Melting point:

147 °C

Boiling point:

354.2±25.0 °C(Predicted)

Density 

1.665±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

4.35±0.40(Predicted)

color 

Pale Brown

CAS DataBase Reference

21816-08-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39-37/39

WGK Germany 

3

RTECS 

AU4452500

HazardClass 

IRRITANT

HS Code 

2916200090

3-Bromoadamantane-1-carboxylic acid Usage And Synthesis

Uses

3-Bromo-1-adamantane Carboxylic Acid is used in the synthesis and in bioactivity of novel adamantyl derivatives, as potent MDR reversal agents.

Purification Methods

Purify the acid by recrystallising it from cyclohexane and/or subliming at 130o/10mm. It is converted to the methyl ester (diazomethane) with m 32o (from pet ether at -10o). [Stetter & Mayer Chem Ber 95 667 1962, Stetter & Wulff Chem Ber 93 1366 1960, Bayal & Lantvoev J Org Chem USSR (Engl Trans) 9 291 1973.]

3-Bromoadamantane-1-carboxylic acid(21816-08-0)Related Product Information

• Citric acid
• Ethyl 2-(Chlorosulfonyl)acetate
• 4-Bromomethylbenzoic acid
• Folic acid
• Adamantane
• 2-Adamantanone
• Amantadine
• 1-Adamantanecarboxylic acid
• Ascoric Acid
• Bromocyclohexane
• Cyclooctanecarbaldehyde
• 8-Bromooctanoic acid
• 4-Bromobutyric acid
• CYCLOOCTYL BROMIDE
• 6-Bromo-1-hexanol
• 8-Bromo-1-octanol
• 2-CYCLOHEXYLETHYL BROMIDE
• CYCLOOCTANEMETHANOL