Basic information Safety Supplier Related

DL-alpha-Methylbenzylamine

Basic information Safety Supplier Related

DL-alpha-Methylbenzylamine Basic information

Product Name:
DL-alpha-Methylbenzylamine
Synonyms:
  • AKOS BBS-00003709
  • ALPHA-METHYLBENZYLAMINE
  • ALPHA-PEA
  • ALPHA-PHENYL ETHYLAMINE
  • DL-A-PHENYLETHYLAMINE
  • DL(+/-)-ALPHA-METHYLBENZYLAMINE
  • DL-ALPHA-METHYLBENZYLAMINE
  • DL-ALPHA-PHENYLETHYLAMINE
CAS:
618-36-0
MF:
C8H11N
MW:
121.18
EINECS:
210-545-8
Product Categories:
  • Pharmaceutical intermediates
Mol File:
618-36-0.mol
More
Less

DL-alpha-Methylbenzylamine Chemical Properties

Melting point:
-65 °C
Boiling point:
185 °C756 mm Hg(lit.)
Density 
0.94 g/mL at 25 °C(lit.)
vapor pressure 
0.7 hPa (20 °C)
refractive index 
n20/D 1.526(lit.)
Flash point:
175 °F
storage temp. 
Store below +30°C.
solubility 
42g/l
form 
Liquid
pka
9.04±0.10(Predicted)
color 
Clear colorless to light yellow
Water Solubility 
4.2 g/100 mL (20 ºC)
Sensitive 
Air Sensitive
Merck 
14,6026
BRN 
636127
Dielectric constant
4.4(18℃)
Stability:
Stable, but absorbs carbon dioxide from the air. Store under an inert atmosphere. Incompatible with strong oxidizing agents, carbon dioxide.
InChIKey
RQEUFEKYXDPUSK-UHFFFAOYSA-N
LogP
1.31 at 25℃
CAS DataBase Reference
618-36-0(CAS DataBase Reference)
NIST Chemistry Reference
Benzenemethanamine, «alpha»-methyl-, (.+/-.)-(618-36-0)
EPA Substance Registry System
Benzenemethanamine, .alpha.-methyl- (618-36-0)
More
Less

Safety Information

Hazard Codes 
C
Risk Statements 
21/22-34
Safety Statements 
26-28-36/37/39-45-28A
RIDADR 
UN 2735 8/PG 2
WGK Germany 
1
RTECS 
DP5775000
10-23
Autoignition Temperature
355 °C
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29214980

MSDS

More
Less

DL-alpha-Methylbenzylamine Usage And Synthesis

Chemical Properties

liquid

Uses

Used for synthesis and as an emulsifying agent; used as a resolving agent and chiral intermediate.

Uses

α-Methylbenzylamine can be used as a reactant for the synthesis of dihydro-5H-dibenz[c,e]azepinium salts by reacting with racemic biphenol derivatives.

Definition

ChEBI: A phenylethylamine that is ethylamine substituted by a phenyl group at position 1.

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 4272, 1984 DOI: 10.1021/jo00196a031
Chemical and Pharmaceutical Bulletin, 36, p. 1529, 1988 DOI: 10.1248/cpb.36.1529
Tetrahedron Letters, 27, p. 3957, 1986 DOI: 10.1016/S0040-4039(00)84883-2

General Description

α-Methylbenzylamine is a nitrogen source that is widely used as a representative substrate to study the chemo-enzymatic kinetic resolution of primary amines.

Flammability and Explosibility

Non flammable

Purification Methods

Dissolve the amine in toluene, dry over NaOH and distil; fraction boiling at 187-188o/atm is collected. Store it under N2 to avoid forming the carbamate and urea. Similarly for the S-(-) enantiomer [2627-86-3]. [Ingersoll Org Synth Coll Vol II 503 1943, Robinson & Snyder Org Synth Coll Vol III 717 1955, Beilstein 12 IV 2424, 2425.]

DL-alpha-Methylbenzylamine Preparation Products And Raw materials

Preparation Products

Raw materials

DL-alpha-MethylbenzylamineSupplier

Jiangxi Boye Medical Technology Co., Ltd Gold
Tel
15387090420 15387090420
Email
2684361091@qq.com
Changsha Jing Kang New Material Technology Co., Ltd. Gold
Tel
0731-85118349 18874718518
Email
ma_haihong@sina.com
Taian Jiayue Bio-chemical Co. LTD Gold
Tel
15318151873
Email
285424065@qq.com
Qingdao Dexin Chemical Co., Ltd Gold
Tel
15564477061
Email
1397986535@qq.com
NanJing JingWei Chemical Co., Ltd. Gold
Tel
13270709979
Email
njjwchem@163.com