Basic information Safety Supplier Related

4-[(3-FLUOROBENZYL)OXY]BENZENECARBOXYLIC ACID

Basic information Safety Supplier Related

4-[(3-FLUOROBENZYL)OXY]BENZENECARBOXYLIC ACID Basic information

Product Name:
4-[(3-FLUOROBENZYL)OXY]BENZENECARBOXYLIC ACID
Synonyms:
  • 4-[(3-FLUOROBENZYL)OXY]BENZENECARBOXYLIC ACID
  • 4-[(3-FLUOROBENZYL)OXY]BENZOIC ACID
  • ASINEX-REAG BAS 13355063
  • TIMTEC-BB SBB010215
  • 4-[(3-fluorophenyl)methoxy]benzoic acid
  • 4-[(3-fluorophenyl)methoxy]benzoate
  • Safinamide Impurity E
  • Safinamide Impueity C
CAS:
405-85-6
MF:
C14H11FO3
MW:
246.23
Mol File:
405-85-6.mol
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4-[(3-FLUOROBENZYL)OXY]BENZENECARBOXYLIC ACID Chemical Properties

Melting point:
194-196°C
Boiling point:
393.4±22.0 °C(Predicted)
Density 
1.289±0.06 g/cm3(Predicted)
solubility 
Ethanol: Slightly soluble
pka
4.40±0.10(Predicted)
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Safety Information

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2918999090
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4-[(3-FLUOROBENZYL)OXY]BENZENECARBOXYLIC ACID Usage And Synthesis

Uses

4-[(3-Fluorobenzyl)oxy]benzoic acid is a metabolite of Safinamide. Safinamide is a potent and selective MAO-B inhibitor, and is used as an add-on treatment to treat Parkinson’s disease.

References

[1] LIANGYU ZOU. Identification, Characterization, and Quantification of Impurities of Safinamide Mesilate: Process-Related Impurities and Degradation Products.[J]. Journal of AOAC International, 2017, 120 6: 1029-1037. DOI: 10.5740/jaoacint.16-0218

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