SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE Chemical Properties

Density 

1.47±0.1 g/cm3(Predicted)

storage temp. 

−20°C

form 

White to off-white solid

pka

3.56±0.10(Predicted)

color 

White to off-white

biological source

rabbit

Water Solubility 

Soluble to 0.90 mg/ml in sterile water

Safety Information

Hazard Codes 

T

Risk Statements 

61

Safety Statements 

53-45

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE Usage And Synthesis

Uses

TRAP-14 (SFLLRNPNDKYEPF) is a synthetic thrombin receptor agonist peptide.

Biological Activity

Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe has contractile effects on vascular and gastric smooth muscle. It stimulates the hydrolysis of phosphoinositides.', 'Thrombin receptor activator

storage

Store at -20°C

References

[1] Sugama Y, et al. Thrombin receptor 14-amino acid peptide mediates endothelial hyperadhesivity and neutrophil adhesion by P-selectin-dependent mechanism. Circ Res. 1992 Oct;71(4):1015-9. DOI:10.1161/01.res.71.4.1015
[2] Sabo T, et al. Structure-activity studies of the thrombin receptor activating peptide. Biochem Biophys Res Commun. 1992 Oct 30;188(2):604-10. DOI:10.1016/0006-291x(92)91099-c
[3] Maruyama Y, et al. Thrombin receptor agonist peptide decreases thrombomodulin activity in cultured human umbilical vein endothelial cells. Biochem Biophys Res Commun. 1994 Mar 30;199(3):1262-9. DOI:10.1006/bbrc.1994.1367

SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE(137339-65-2)Related Product Information

• BZ-PHE-VAL-ARG-AMC
• TRAP-6
• H-SER-PHE-LEU-LEU-ARG-ASN-PRO-OH
• FLLRN
• Thrombin
• H-SER-PHE-LEU-LEU-ARG-NH2
• SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE
• H-PRO-PHE-OH
• H-SER-PHE-LEU-LEU-ARG-ASN-NH2
• H-GLU-GLY-PHE-OH
• H-SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE-NH2
• PHE-GLY-GLY-PHE
• 5-OXO-5-PYRROLIDIN-1-YL-PENTANOIC ACID
• LEUPEPTIN