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4-Aminobenzamidine dihydrochloride

Basic information Safety Supplier Related

4-Aminobenzamidine dihydrochloride Basic information

Product Name:
4-Aminobenzamidine dihydrochloride
Synonyms:
  • 4-AMINOBENZAMIDINE DIHYDROCHLORIDE
  • 4-AMINOBENZAMIDINE HCL SALT
  • BENZENECARBOXIMIDAMIDE, 4-AMINO-, DIHYDROCHLORIDE
  • P-AMINOBENZAMIDINE DIHCL
  • P-AMINOBENZAMIDINE DIHYDROCHLORIDE
  • 4-Aminobenzamidine HCl
  • 4-AMINOBENZAMIDINE DIHYDROCHLORIDE, FOR FLUORESCENCE
  • 4-Aminobenzamidine2HCl
CAS:
2498-50-2
MF:
C7H11Cl2N3
MW:
208.09
EINECS:
219-692-2
Product Categories:
  • inhibitor
  • Imines/AmidinesFluorescent Probes, Labels, Particles and Stains
  • Anilines, Aromatic Amines and Nitro Compounds
  • Nitrogen Compounds
  • Organic Building Blocks
  • Other Fluorescent Labels
  • Amines
  • Miscellaneous
  • Broad Spectrum Inhibitors of Proteolytic Enzyme Classes
  • Other Fluorescent LabelsEnzyme Inhibitors
  • Protease InhibitorsFluorescent Stains
  • Protein Stains
  • Protein Stains For SpectroscopyProtease Inhibitors
  • Serine Protease Inhibitors
  • Fluorescent Labels
  • Fluorescent Probes, Labels, Particles and Stains
  • Protease Inhibitors
Mol File:
2498-50-2.mol
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4-Aminobenzamidine dihydrochloride Chemical Properties

Melting point:
>300 °C(lit.)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Water
form 
Fine Crystalline Powder
color 
White to yellow
Sensitive 
Hygroscopic
BRN 
3692927
Stability:
Hygroscopic
InChIKey
GHEHNICLPWTXJC-UHFFFAOYSA-N
CAS DataBase Reference
2498-50-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-37/39-36
WGK Germany 
3
RTECS 
CV6126500
3-10-21
HS Code 
29252900

MSDS

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4-Aminobenzamidine dihydrochloride Usage And Synthesis

Chemical Properties

white to yellowish fine crystalline powder

Uses

4-Aminobenzamidine dihydrochloride is a synthetic diamidine derivative that acts as a urokinase inhibitor as well as trypsin inhibitor. It is used as a ligand in affinity chromatography for purification and immobilization of enzymes.

Application

4-Aminobenzamidine dihydrochloride can be used to synthesize:
Orally active fibrinogen receptor antagonists based on benzamidines.
Benzamidine derivatives that are selective and potent serine protease inhibitors.
Novel pyrrolo [3,2-c] quinolines that are structural analogs of topoisomerase inhibitors such as coralyne and fagaronine.
Synthesis of a selective inhibitor of PRMT1 (SKLB-639)

Preparation

4-Aminobenzamididine dihydrochloride is obtained by cyanation, addition, amination and reduction of 4-nitrobenzoic acid.

Definition

ChEBI: P-Aminobenzamidine dihydrochloride is an organic molecular entity.

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