ChemicalBook > Product Catalog > Organic Chemistry > Amides > Amides > 2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide
2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide
2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide Basic information
- Product Name:
- 2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide
- Synonyms:
-
- 2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide
- ML251
- 2-(3,4-Dichlorophenyl)-N-(4-(N-(isoxazol-3-yl)sulfamoyl)phenyl)acetamide
- cruzi,inhibit,brucei,MRC-5,Inhibitor,nanomolar,Parasite,ML-251,ML 251,ML251
- CAS:
- 1486482-16-9
- MF:
- C17H13Cl2N3O4S
- MW:
- 426.27382
- Mol File:
- 1486482-16-9.mol
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2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO : 250 mg/mL (586.48 mM; Need ultrasonic)
- form
- Solid
- color
- White to off-white
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2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide Usage And Synthesis
Biological Activity
ML251, a potent nanomolar T. brucei and T. cruzi phosphofructokinase (PFK) inhibitor, inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1]. ML251 (T. brucei; 0~33.3 μg/mL) produces modest dose-dependent toxicity[1].
References
[1]. Brimacombe KR, et al. Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase. ACS Med Chem Lett. 2013;5(1):12-17.
2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamideSupplier
Shanghai Lollane Biological Technology Co.,Ltd.
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- 021-52996696，15000506266 15000506266
Shanghaizehan biopharma technology co., Ltd.
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- 021-61350663 13052117465
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Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel
- 15076683720
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ShangHai Biochempartner Co.,Ltd
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- 177-54423994 17754423994
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Shanghai Rechem science Co., Ltd.
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- 21-31433387 15618786686
- sales@rechemscience.com
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2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide(1486482-16-9)Related Product Information
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