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ERYTHROSIN B

Basic information Safety Supplier Related

ERYTHROSIN B Basic information

Product Name:
ERYTHROSIN B
Synonyms:
  • 2’,4’,5’,7’-tetraiodo-fluorescei
  • 2’,4’,5’,7’-tetraiodofluorescein
  • 3’,6’-Dihydroxy-2’,4’,5’,7’-tetraiodospiro[iso-benzofuran-1(3H),9’-[9H]xanthen]-3-onedisodiumsalt
  • 9’-(9h)xanthen)-3-one,3’,6’-dihydroxy-2’,4’,5’,7’-spiro(isobenzofuran-1(3h
  • 9’-[9H]xanthen]-3-one,3’,6’-dihydroxy-2’,4’,5’,7’-tetraiodo-Spiro[isobenzofuran-1(3H)
  • erythrosineacid
  • iodeosin
  • Erythrosin B, spirit soluble, pure, 95%
CAS:
15905-32-5
MF:
C20H8I4O5
MW:
835.89
EINECS:
240-046-0
Product Categories:
  • Inhibitors
  • Organics
Mol File:
15905-32-5.mol
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ERYTHROSIN B Chemical Properties

Melting point:
303 °C (dec.)(lit.)
Boiling point:
628.3±55.0 °C(Predicted)
Density 
2.4391 (estimate)
storage temp. 
room temp
solubility 
spirit: soluble
form 
powder
pka
7.21±0.20(Predicted)
Colour Index 
45430:2
color 
Red
Water Solubility 
Soluble in water, spirit, methanol, methyl cellosolve and ethanol.
EPA Substance Registry System
2',4',5',7'-Tetraiodofluorescein (15905-32-5)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
2
RTECS 
LM5940000
TSCA 
Yes
HS Code 
29329990
Toxicity
A food color formerly approved for use in the United States and Europe. It was used primarily in jams and marmalades, maraschino cherries, pickles and relishes, etc. The LD50 in rats is 150 mg/kg, i.p., and 600 mg/kg, p.o. Erythrosine has a variety of actions in vitro due in large measure to its ability to affect biological membranes and lipophilic sites of enzymes. Such data have led to the hypothesis that erythrosine could be neurotoxic, but both clinical and preclinical data have suggested that erythrosine is not likely to be neurotoxic at doses that might be encountered. Two other toxicological issues have been raised with this food color. It has been suggested to be a potential, if weak, carcinogen, and it may also contribute to potential thyroid toxicity resulting from release of iodine.

MSDS

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ERYTHROSIN B Usage And Synthesis

Chemical Properties

orange-red fine powder

Uses

Indicator in analytical chemistry.

Uses

Erythrosin B is used as a red coloring in some foods such as cherries and fish. It is used as printing ink, dental plaque disclosing agent and biological stain. It finds application as a radiopaque medium and sensitizer for orthochromatic photographic films. It is utilized as a cake-decorating gel. In addition to this, it is used in sweets such as candies and popsicles.

Uses

Erythrosin B has been used as a dye in fluorescence lifetime imaging.

Preparation

Fluorescein (C.I.Acid Yellow 73, C.L 45350) in aqueous solution or Tetraiodide in ethanol, and made ??the free acid form.

Biochem/physiol Actions

Erythrosin B, also called as eosin B, is a xanthene dye. It belongs to the family of fluorescein dyes. It plays a major role in inhibiting dopamine uptake and high affinity 3H-ouabain binding and ion transport in synaptosomes from rat caudate nucleus.

Properties and Applications

blue light red. Soluble in water for cherry red, no fluorescence. In concentrated sulfuric acid for brown light yellow, dilution after brown light yellow precipitation. Dye aqueous solution to join sodium hydroxide have soluble precipitation. Used in cosmetics coloring.

Standard Light Fastness Heat-resistant(℃) water Sodium Carbonate(5%) Hydrochloric acid(5%)
Melting point Stable
ISO Poor Insoluble

ERYTHROSIN BSupplier

J & K SCIENTIFIC LTD.
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