EVERNIC ACID
EVERNIC ACID Basic information
- Product Name:
- EVERNIC ACID
- Synonyms:
-
- LECANORIC ACID METHYL ETHER
- EVERNIC ACID
- 2-HYDROXY-4-[2-HYDROXY-4-METHOXY-6-METHYLBENZOYLOXY]-6-METHYLBENZOIC ACID
- 6-cresoticacid,4-methoxy-4-esterwith6-methyl-beta-resorcylate
- 6-cresoticacid,4-methoxy-4-esterwith6-methyl-beta-resorcylicacid
- benzoicacid,2-hydroxy-4-((2-hydroxy-4-methoxy-6-methylbenzoyl)oxy)-6-methyl
- 4-[(4-methoxy-6-methylsalicyloyl)oxy]-6-methylsalicylic acid
- EVERNIC ACID YELLOW CRYSTALS
- CAS:
- 537-09-7
- MF:
- C17H16O7
- MW:
- 332.3
- EINECS:
- 208-658-2
- Product Categories:
-
- Plant Oils, Toxins, Phenolic Acids & Derivatives
- Mol File:
- 537-09-7.mol
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EVERNIC ACID Chemical Properties
- Melting point:
- 166-167°C
- solubility
- DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 0.5 mg/ml
- form
- A crystalline solid
- LogP
- 5.030 (est)
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EVERNIC ACID Usage And Synthesis
Description
Evernic acid is a secondary metabolite produced by some species of lichen that can bind to allosteric sites on the protein surface of FAS-II enzymes and produce antibacterial and antiplasmodial effects. It inhibits two key plasmodial FAS-II enzymes PfFabZ and PfFabI (IC50 = 10.7 and 36.1 μM, respectively) but shows low efficacy against the malaria parasite P. berghei (IC50 = 77.3 μM).
Definition
ChEBI: 2-hydroxy-4-[(2-hydroxy-4-methoxy-6-methylphenyl)-oxomethoxy]-6-methylbenzoic acid is a carbonyl compound.
EVERNIC ACIDSupplier
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Chengdu Push Bio-Technology Co., Ltd.
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Shanghai Jizhi Biochemical Technology Co. Ltd.
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