(RS)-3,5-DHPG Chemical Properties

Boiling point:

448.8±33.0 °C(Predicted)

Density 

1.550±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMSO: 1 mg/ml; Water: 1 mg/ml

form 

A solid

pka

1.77±0.10(Predicted)

color 

White

Water Solubility 

Soluble in water (10mM)

Stability:

Hygroscopic

(RS)-3,5-DHPG Usage And Synthesis

Uses

(RS)-3,5-DHPG is a selective group I metabotropic glutamate receptor agonist which activates both mGluR1 and mGluR5. It has been shown that (RS)-3,5-DHPG can modulate Kir4.1 protein and mRNA in cultured rat retinal Müller cells.(RS)-3,5-DHPG acts as a potential target in treatment of parkinson''s disease.

Definition

ChEBI: A glycine derivative that is L-alpha-phenylglycine substituted at positions 3 and 5 on the phenyl ring by hydroxy groups.

storage

-20°C (desiccate). Protect from light.

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