tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu Basic information
- Product Name:
- tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu
- Synonyms:
-
- (S)-22-(Tert-butoxycarbonyl)-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontane-1,41-dioic acid
- Octadecane(OtBu)-Glu(ɑ-OtBu)-AEEA-AEEA-OH
- Side chain
- tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu
- Semaglutide side chain
- Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OHu
- (S)-22-(tert-butoxycarbonyl)-43,43-dimethyl-10,19,24,41-tetraoxo-3,6,12,15,42-pentaoxa-9,18,23-triazatetratetracontanoic acid
- Egf(a) analogue-13C4
- CAS:
- 1118767-16-0
- MF:
- C43H79N3O13
- MW:
- 846.1
- Mol File:
- 1118767-16-0.mol
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu Chemical Properties
- Boiling point:
- 940.6±65.0 °C(Predicted)
- Density
- 1.079±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place, Sealed in dry, Store in freezer, under -20°C
- pka
- 3.39±0.10(Predicted)
- InChIKey
- YZUXNRZPWYRMGH-DHUJRADRSA-N
- SMILES
- C(O)(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](C(OC(C)(C)C)=O)NC(=O)CCCCCCCCCCCCCCCCC(OC(C)(C)C)=O
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu Usage And Synthesis
Description
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu is the 18-carbon fatty acid side chain of somatostatin, which contributes to an increased affinity for albumin (approximately 5-6 fold). Somalutide is a glucagon-like peptide-1 (GLP-1) analogue with hypoglycaemic properties.
Uses
(S)-22-(Tert-butoxycarbonyl)-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontane-1,41-dioic acid can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and chemical production processes.
Definition
TBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu is also known as Semaglutide Side Chain. An 18-carbon fatty acid side chain of semaglutide. The affinity of the semaglutide side chain for albumin was enhanced 5-6 times. Semaglutide is a glucagon-like peptide-1 (GLP-1) analog with significant hypoglycemic efficacy.
Application
OLED intermediates, Pharmaceutical Raw Intermediates, Fine Chemical Intermediate
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