1-(4,6-dimethylpyrimidin-2-yl)-3-[2-(trifluoromethyl)phenyl]guanidine Chemical Properties

Melting point:

149-151 °C

Boiling point:

404.3±55.0 °C(Predicted)

Density 

1.35±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMSO : 25 mg/mL (80.83 mM; ultrasonic and warming and heat to 60°C)

pka

4.69±0.70(Predicted)

1-(4,6-dimethylpyrimidin-2-yl)-3-[2-(trifluoromethyl)phenyl]guanidine Usage And Synthesis

Uses

ZINC 69391 is a novel specific Rac1 inhibitor, interferring with the interaction of Rac1 with Dock180, a relevant Rac1 activator in glioma invasion, and to reduce Rac1-GTP levels.