Vidarabine monophosphate
Vidarabine monophosphate Basic information
- Product Name:
- Vidarabine monophosphate
- Synonyms:
-
- 9H-Purin-6-amine,9-(5-O-phosphono-b-D-arabinofuranosyl)-
- ARA-AMP
- 9-BETA-D-ARABINOFURANOSYLADENINE-5'-MONOPHOSPHATE
- 9-BETA-D-ARABINOFURANOSYL-ADENINE-5'-MONOPHOSPHORIC ACID
- 9-BETA-D-ARABINOFURANOSYLADENINE MONOPHOSPHATE
- 9-(5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE
- ADENINE-9-BETA-D-ARABINOFURANOSIDE-5'-MONOPHOSPHATE
- ADENINE-BETA-D-ARABINOFURANOSIDE-5'-PHOSPHATE
- CAS:
- 29984-33-6
- MF:
- C10H14N5O7P
- MW:
- 347.22
- EINECS:
- 249-990-8
- Product Categories:
-
- 29984-33-6
- Mol File:
- 29984-33-6.mol
Vidarabine monophosphate Chemical Properties
- Melting point:
- 213 °C
- Boiling point:
- 798.5±70.0 °C(Predicted)
- Density
- 2.32±0.1 g/cm3(Predicted)
- storage temp.
- Store at 0°C
- form
- Powder
- pka
- 1.86±0.10(Predicted)
- color
- White to Off-white
- Water Solubility
- Soluble in water at 4mg/ml
Safety Information
- Hazard Codes
- Xn,T,Xi
- Risk Statements
- 20/22-40-23/24/25-36/37/38
- Safety Statements
- 37/39-24/25-45-36/37/39-22-36-26
- RIDADR
- 2811
- RTECS
- AU6204000
- HazardClass
- 6.1(a)
- PackingGroup
- II
- HS Code
- 29400090
- Toxicity
- LD50 ipr-rat: 1700 mg/kg DRFUD4 4,547,79
MSDS
- Language:English Provider:Adenine-9-beta-D-arabinofuranoside-5'-monophosphate
- Language:English Provider:ACROS
Vidarabine monophosphate Usage And Synthesis
Description
Vidarabine monophosphate, chemical name: 9-(5-O-Phosphono-beta-D-arabinofuranosyl)adenine is an anti deoxyribonucleic acid virus drug. IVidarabine triphosphate directly inhibits DNA polymerase and also acts as a chain terminator in DNA replication. An adenosine monophosphate analog in which ribose is replaced by an arabinose moiety. It is the monophosphate ester of VIDARABINE with antiviral and possibly antineoplastic properties.
Chemical Properties
Crystalline
Uses
Antiviral.
Uses
Disrupts viral DNA synthesis. Competitive viral DNA polymerase inhibitor. Active against herpes simplex and varicella zoster viruses in vivo.
Application
Vidarabine monophosphate has broad-spectrum anti-virus effect and can inhibit a variety of DNA viruses. It is mainly used to treat chronic hepatitis B and other viral infections, such as herpes zoster, herpes simplex and genital herpes. It has quick effect and clear curative effect. It is a common drug for clinical anti-virus treatment.
Safety Profile
Moderately toxic byintraperitoneal route. When heated to decomposition itemits very toxic fumes of POx and NOx.
Vidarabine monophosphateSupplier
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Vidarabine monophosphate(29984-33-6)Related Product Information
- Cytarabine
- Bis(2-ethylhexyl)amine
- Alkaline Phosphatase
- Vidarabine
- Aniline
- Adenine
- Sodium Monofluorophosphate
- Acetyl hypoxanthine
- Iodixanol
- PotassiuM sodiuM Dehydroandrographolide Succinate
- 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-Benzofurancarboxylic acid
- 2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
- Adenosine
- Fludarabine phosphate
- Vidarabine monophosphate
- ADENINE-BETA-D-ARABINOFURANOSIDE 5'-MONOPHOSPHATE, DIAMMONIUM SALT, [2,8-3H]-
- 6-BENZYLOXYAMINO-9-(5-O-DIPHENYLPHOSPHONO-BETA-D-ARABINOFURANOSYL)-2-FLUORO-9H-PURINE
- 2-FLUORO-6-(1,2,4-TRIAZOL-1-YL)-9-(5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-9H-PURINE