Triacetonamine
Triacetonamine Basic information
- Product Name:
- Triacetonamine
- Synonyms:
-
- LABOTEST-BB LT00159409
- TETRAMETHYLPIPERIDINONE
- TAA
- 2,2,6,6-TETRAMETHYLTETRAHYDRO-4(1H)-PYRIDINONE
- 2,2,6,6-TETRAMETHYL-PIPERIDIN-4-ONE
- 2,2,6,6-TETRAMETHYL-4-PIPERIDINONE
- 2,2,6,6-TETRAMETHYL-4-PIPERIDONE
- 2,2,6,6-Tetramethyl-4-oxopiperidine
- CAS:
- 826-36-8
- MF:
- C9H17NO
- MW:
- 155.24
- EINECS:
- 212-554-2
- Product Categories:
-
- Heterocycles
- Miscellaneous Reagents
- API intermediates
- Industrial/Fine Chemicals
- Nitrogen cyclic compounds
- 826-36-8
- Mol File:
- 826-36-8.mol
Triacetonamine Chemical Properties
- Melting point:
- 59-61 °C
- Boiling point:
- 105-105°C/18mm
- Density
- 0.9796 (rough estimate)
- refractive index
- 1.4680 (estimate)
- Flash point:
- 73°C
- storage temp.
- 2-8°C
- solubility
- DMSO, Methanol
- pka
- 9.20±0.60(Predicted)
- form
- Solid
- color
- Pale Orange to Light Brown
- Water Solubility
- 249g/L at 20℃
- LogP
- 1.32 at 25℃
- CAS DataBase Reference
- 826-36-8(CAS DataBase Reference)
- NIST Chemistry Reference
- 4-Piperidinone, 2,2,6,6-tetramethyl-(826-36-8)
- EPA Substance Registry System
- 4-Piperidinone, 2,2,6,6-tetramethyl- (826-36-8)
Safety Information
- Hazard Codes
- C,Xn
- Risk Statements
- 34-22-36/37/38
- Safety Statements
- 45-36/37/39-26-22-36/37
- WGK Germany
- 2
- RTECS
- TO0127900
- HS Code
- 29333990
MSDS
- Language:English Provider:2,2,6,6-Tetramethyl-4-piperidone
- Language:English Provider:ACROS
Triacetonamine Usage And Synthesis
Triacetone amine
Triacetonamine has anti-arrhythmic and anti-myocardial ischemia effect.
Take Triacetonamine as raw materials, ethanol as the solvent, perform hydrogenation reaction in the presence of catalyst (normal pressure or 3~4MPa) and obtain raw material of histamine-type light stabilizer 2,2,6,6-tetramethyl-4-piperidinol.
.
Chemical Properties
It appears as white or light yellow powder with the melting point being 43 ℃ and boiling point being 205 ℃. It is soluble in acetone, alcohol, ether and water.
The above information is edited by the chemicalbook of Dai Xiongfeng.
Uses
The product is the intermediate and pharmaceutical intermediate of histamine light stabilizer. Itself also has light-stabilizing effect. It has important application in pharmaceuticals.
Chemical Properties
white crystalline powder
Uses
2,2,6,6-Tetramethyl-4-piperidinone (cas# 826-36-8) is a compound useful in organic synthesis.
Definition
ChEBI: Triacetonamine is a member of piperidones.
Synthesis Reference(s)
Synthesis, p. 735, 1976 DOI: 10.1055/s-1976-24178
in vivo
Triacetonamine (Purchased from MCE; 200 mg, 300 mg, 400 mg/Kg/day; gavage; 2 days) shows typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality[2].
| Animal Model: | Rats (half male and female, 6-8 weeks old, 200?±?10 g)[2] |
| Dosage: | 200 mg, 300 mg, 400 mg/Kg |
| Administration: | Gavage; daily; 2 days |
| Result: | Showed typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality. |
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Triacetonamine(826-36-8)Related Product Information
- 2,2,6,6-Tetramethylpiperidinooxy
- Triacetoneamino Alcohol TAA-ol,TAA-OL
- Diethylenetriamine
- Norgestrel
- Triacetonediamine
- 4-Piperidinone
- 1-Methyl-4-piperidone
- 2,2,6,6-Tetramethylpiperidine
- 4-Methyl-2-pentanone
- Pyruvic acid
- Tamoxifen
- Calcium pyruvate
- Mesotrione
- Acetylacetone
- PIPERONYL METHYL KETONE
- Propiophenone
- Phenylacetone
- 2,2,6,6-Tetramethyl-4-Piperidone/Tripyruvalamine