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5-Methoxy-2-nitrobenzoic acid

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5-Methoxy-2-nitrobenzoic acid Basic information

Product Name:
5-Methoxy-2-nitrobenzoic acid
Synonyms:
  • 2-nitro-5-methoxybenzoic acid
  • 5-METHOXY-2-NITROBENZOIC ACID
  • 6-Nitro-m-anisicacid
  • (R)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE 98+%
  • 5-Methoxy-2-nitrobenzoic acid,97%
  • 6-Nitro-m-anisic acid, 2-Carboxy-4-methoxynitrobenzene
  • 5-Methoxy-nitrobenzoic Acid
  • 6-Nitro-m-anisic acid, 2-Carboxy-4-methoxyn
CAS:
1882-69-5
MF:
C8H7NO5
MW:
197.14
Product Categories:
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • C8
  • blocks
  • Carboxes
  • Carbonyl Compounds
  • Carboxylic Acids
  • NitroCompounds
  • Acids and Derivatives
Mol File:
1882-69-5.mol
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5-Methoxy-2-nitrobenzoic acid Chemical Properties

Melting point:
125-130 °C (lit.)
Boiling point:
334.23°C (rough estimate)
Density 
1.430
refractive index 
1.5700 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
pka
2.06±0.25(Predicted)
form 
Granules
color 
Beige to gray or brown
BRN 
1877657
InChIKey
URADKXVAIGMTEG-UHFFFAOYSA-N
CAS DataBase Reference
1882-69-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26-37
WGK Germany 
3
HS Code 
29182900

MSDS

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5-Methoxy-2-nitrobenzoic acid Usage And Synthesis

Chemical Properties

beige to grey or brown granules

Uses

5-Methoxy-nitrobenzoic Acid is used in the synthesis of Cathepsin S inhibitors with antitumor applications. In addition, 2-aminocombretastatin derivatives with potential as antimitotic agents are synthesized using this compound.

Uses

5-Methoxy-2-nitrobenzoic acid may be used as starting material in the synthesis of the following:

  • dictyoquinazol A, a neuroprotective compound
  • 5-methoxyantranilic acid by catalytic reduction
  • pyrrolobenzodiazepines

Uses

5-Methoxy-2-nitrobenzoic acid is used in the synthesis of Cathepsin S inhibitors with antitumor applications. In addition, 2-aminocombretastatin derivatives with potential as antimitotic agents are synt hesized using this compound.

General Description

5-Methoxy-2-nitrobenzoic acid is a substituted 2-nitrobenzoic acid. It has been reported to be one of the microbial degradation metabolite of cypermethrin, a synthetic pyrethroid pesticide.

5-Methoxy-2-nitrobenzoic acid Preparation Products And Raw materials

Raw materials

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