1-Naphthylacetonitrile Chemical Properties

Melting point:

33-35 °C(lit.)

Boiling point:

191-194 °C18 mm Hg(lit.)

Density 

1.1110 (rough estimate)

refractive index 

n20/D 1.6192(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Sparingly), Dichloromethane (Slightly), Methanol (Slightly)

form 

Liquid After Melting

color 

Clear yellow to brown

BRN 

1101012

CAS DataBase Reference

132-75-2(CAS DataBase Reference)

NIST Chemistry Reference

1-Naphthaleneacetonitrile(132-75-2)

EPA Substance Registry System

1-Naphthaleneacetonitrile (132-75-2)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38-22

Safety Statements 

26-37/39-24/25-37-36

RIDADR 

3276

WGK Germany 

3

RTECS 

AM1240000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29269090

Toxicity

mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03835,

MSDS

• Language:English Provider:1-Naphthyl acetonitrile
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1-Naphthylacetonitrile Usage And Synthesis

Chemical Properties

White to yellow solid or melt. Insoluble in water.

Uses

2-(Naphthalen-1-yl)acetonitrile is useful for the preparation of tert-Bu benzoates.

Preparation

Synthesis of 1-naphthylacetonitrile: 695g of 1-chloromethyl naphthalene, 1500ml of methanol and 475ml of water, 350g of sodium cyanide mixture boiling reflux, stirring the reaction for 2h. 1300ml of methanol was evaporated, cooled, and the reactants were washed with water to neutral to obtain 670-680g of 1-naphthylacetonitrile.

Application

1-Naphthylacetonitrile is an organic synthesis intermediate. It is used in the synthesis of 1-naphthylacetate.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 39, p. 3030, 1991 DOI: 10.1248/cpb.39.3030

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