Hexyl salicylate Chemical Properties

Boiling point:

290 °C (lit.)

Density 

1.04 g/mL at 25 °C (lit.)

vapor pressure 

0.077Pa at 23℃

refractive index 

n20/D 1.505(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Sparingly), DMSO (Slightly)

pka

8.17±0.30(Predicted)

color 

Colourless oily liquid.

Odor

at 100.00 %. fresh herbal orchid green

Odor Type

herbal

Water Solubility 

0.28g/L(37 ºC)

BRN 

2453103

LogP

5.5 at 30℃

CAS DataBase Reference

6259-76-3(CAS DataBase Reference)

NIST Chemistry Reference

N-hexyl salicylate(6259-76-3)

EPA Substance Registry System

Hexyl salicylate (6259-76-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

UN 3082 9 / PGIII

WGK Germany 

2

RTECS 

DH2207000

Toxicity

Both the acute oral LD₅₀ value in rats and the acute dermal LD₅₀ value in rabbits exceeded 5 g/kg (Moreno, 1975).

MSDS

• Language:English Provider:SigmaAldrich

Hexyl salicylate Usage And Synthesis

Chemical Properties

Colorless and transparent oil liquid

Chemical Properties

Hexyl Salicylate has been reported in carnation flower absolute . It is a colorless liquid with a green, floral, spicy odor, reminiscent of azaleas. It is used for blossom and herbal notes in perfumes, for example, in soaps, personal hygiene products, and detergents.

Occurrence

Has apparently not been reported to occur in nature.

Uses

Hexyl salicylate may be used as an internal standard for the determination of allergenic ester, benzyl salicylate in propolis specimens using gas chromatography-mass spectrometry (GC?MS), high-performance liquid chromatography (HPLC), and ultraviolet-visible (UV?Vis) spectrophotometry. It may also be used as a standard fragrance material for the quantification of the analyte in wastewater treatment plants using gas chromatography-mass spectrometry (GC?MS).

Definition

ChEBI: Hexyl salicylic acid is a benzoate ester.

Preparation

By methyl salicylate exchange with n-hexanol using a sodium methoxylate catalyst.

General Description

Hexyl salicylate belongs to the class of flavor & fragrance standards, for use in food, beverage and cosmetic industry. These standards are widely used to add taste and/or smell to products without aroma, to mask unpleasant odors and to maintain stability of original flavor.

Flammability and Explosibility

Non flammable

Metabolism

Because of the widespread medicinal use of salicyclic acid and its derivatives, there is an extensive literature on the metabolism and excretion of these compounds. Most esters of salicyclic acid hydrolyse to salicylic acid in the body, but this occurs more readily with the lower esters, little of the amyl ester being split. A large proportion of salicylic acid is excreted unchanged by most species; salicyluric acid, gentisic acid, and salicylglucuronides are also known to be excreted (Williams. 1959). Salicylic acid has been found to be teratogenic to rats (Koshakji. 1972).

Hexyl salicylate (6259-76-3)Related Product Information

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