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2'-Deoxycytidine

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2'-Deoxycytidine Basic information

Product Name:
2'-Deoxycytidine
Synonyms:
  • DC
  • CYTOSINE DEOXYRIBOSIDE
  • 1-(2'-DEOXY-BETA-D-RIBOFURANOSYL)CYTOSINE
  • 2'-DC
  • 2'-DEOXY-D-CYTIDINE
  • 4-Amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • 2'-DEOXYCYTIDINE:H2O
  • 4-aMino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-1,2-dihydropyriMidin-2-one
CAS:
207121-53-7
MF:
C9H15N3O5
MW:
245.24
EINECS:
213-454-1
Product Categories:
  • Miscellaneous Biochemicals
Mol File:
207121-53-7.mol
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2'-Deoxycytidine Chemical Properties

Melting point:
209-211 °C(lit.)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White
Stability:
Hygroscopic
InChI
InChI=1/C9H13N3O4.H2O/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8;/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15);1H2/t5-,6+,8+;/s3
InChIKey
HXBGOHZLZCFWLH-AZXCMKNYNA-N
SMILES
O=C1N=C(N)C=CN1[C@H]1C[C@H](O)[C@@H](CO)O1.O |&1:8,10,12,r|
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Safety Information

WGK Germany 
3
RTECS 
HA3800000
10

MSDS

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2'-Deoxycytidine Usage And Synthesis

Uses

A deoxyribonucleoside as Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity.

Definition

ChEBI: 2'-deoxycytidine is a pyrimidine 2'-deoxyribonucleoside having cytosine as the nucleobase. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a cytosine.

Purification Methods

Purify 2'-deoxycytidine by recrystallisation from MeOH/Et2O or EtOH and dry it in air. [NMR: Miles J Am Chem Soc 85 1007 1963, UV: Fox & Shugar Biochim Biophys Acta 9 369 1952.] The hydrochloride crystallises from H2O/EtOH and has m 174o(dec, 169-173o). [Walker & Butler Can J Chem 34 1168 1956.] The picrate has m 208o(dec). [Fox et al. J Am Chem Soc 83 4066 1961, Beilstein 25 III/IV 3662.]

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