2'-Deoxycytidine
2'-Deoxycytidine Basic information
- Product Name:
- 2'-Deoxycytidine
- Synonyms:
-
- DC
- CYTOSINE DEOXYRIBOSIDE
- 1-(2'-DEOXY-BETA-D-RIBOFURANOSYL)CYTOSINE
- 2'-DC
- 2'-DEOXY-D-CYTIDINE
- 4-Amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- 2'-DEOXYCYTIDINE:H2O
- 4-aMino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-1,2-dihydropyriMidin-2-one
- CAS:
- 207121-53-7
- MF:
- C9H15N3O5
- MW:
- 245.24
- EINECS:
- 213-454-1
- Product Categories:
-
- Miscellaneous Biochemicals
- Mol File:
- 207121-53-7.mol
2'-Deoxycytidine Chemical Properties
- Melting point:
- 209-211 °C(lit.)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White
- Stability:
- Hygroscopic
- InChI
- InChI=1/C9H13N3O4.H2O/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8;/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15);1H2/t5-,6+,8+;/s3
- InChIKey
- HXBGOHZLZCFWLH-AZXCMKNYNA-N
- SMILES
- O=C1N=C(N)C=CN1[C@H]1C[C@H](O)[C@@H](CO)O1.O |&1:8,10,12,r|
Safety Information
- WGK Germany
- 3
- RTECS
- HA3800000
- F
- 10
MSDS
- Language:English Provider:SigmaAldrich
2'-Deoxycytidine Usage And Synthesis
Uses
A deoxyribonucleoside as Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity.
Definition
ChEBI: 2'-deoxycytidine is a pyrimidine 2'-deoxyribonucleoside having cytosine as the nucleobase. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a cytosine.
Purification Methods
Purify 2'-deoxycytidine by recrystallisation from MeOH/Et2O or EtOH and dry it in air. [NMR: Miles J Am Chem Soc 85 1007 1963, UV: Fox & Shugar Biochim Biophys Acta 9 369 1952.] The hydrochloride crystallises from H2O/EtOH and has m 174o(dec, 169-173o). [Walker & Butler Can J Chem 34 1168 1956.] The picrate has m 208o(dec). [Fox et al. J Am Chem Soc 83 4066 1961, Beilstein 25 III/IV 3662.]
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