2-(2,3-DIHYDRO-2-METHOXY-1,4-BENZODIOXIN-2-YL)-4,5-DIHYDRO-1H-IMIDAZOLE HYDROCHLORIDE
2-(2,3-DIHYDRO-2-METHOXY-1,4-BENZODIOXIN-2-YL)-4,5-DIHYDRO-1H-IMIDAZOLE HYDROCHLORIDE Basic information
- Product Name:
- 2-(2,3-DIHYDRO-2-METHOXY-1,4-BENZODIOXIN-2-YL)-4,5-DIHYDRO-1H-IMIDAZOLE HYDROCHLORIDE
- Synonyms:
-
- 2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride
- 2-(2,3-DIHYDRO-2-METHOXY-1,4-BENZODIOXIN-2-YL)-4,5-DIHYDRO-1H-IMIDAZOLE HYDROCHLORIDE
- RX 821002 HYDROCHLORIDE
- 2-[2-(2-Methoxy-1,4-benzodioxanyl)]imidazoline hydrochloride
- 2-(3-methoxy-2h-1,4-benzodioxin-3-yl)-4,5-dihydro-1h-imidazole,hydrochloride
- (S)-2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride
- 2-Methoxyidazoxan monohydrochloride
- 2-(2-Methoxy-2,3-Dihydro-1,4-Benzodioxin-2-Yl)-4,5-Dihydro-1H-Imidazole Hydrochloride (1:1)
- CAS:
- 109544-45-8
- MF:
- C12H15ClN2O3
- MW:
- 270.71
- Mol File:
- 109544-45-8.mol
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2-(2,3-DIHYDRO-2-METHOXY-1,4-BENZODIOXIN-2-YL)-4,5-DIHYDRO-1H-IMIDAZOLE HYDROCHLORIDE Chemical Properties
- storage temp.
- Desiccate at RT
- solubility
- H2O: >20mg/mL
- form
- solid
- color
- white
- Water Solubility
- H2O: >20mg/mL
- InChI
- 1S/C12H14N2O3.ClH/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12;/h2-5H,6-8H2,1H3,(H,13,14);1H
- InChIKey
- IMPOOMVZVWKSAP-UHFFFAOYSA-N
- SMILES
- Cl[H].COC1(COc2ccccc2O1)C3=NCCN3
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2-(2,3-DIHYDRO-2-METHOXY-1,4-BENZODIOXIN-2-YL)-4,5-DIHYDRO-1H-IMIDAZOLE HYDROCHLORIDE Usage And Synthesis
Uses
RX 821002 Hydrochloride is a selective and potent α2-adrenoceptor antagonist.
Biochem/physiol Actions
Selective α2-adrenoceptor antagonist
in vivo
2-Methoxyidazoxan monohydrochloride (1 mg/kg) enhances locomotion in the novel environment, particularly in neonatal ventral hippocampal lesion (NVHL) rats. RX82100 has a biphasic effect on locomotion, consisting of an initial reduction preceding the enhancement[3].
storage
Desiccate at RT
2-(2,3-DIHYDRO-2-METHOXY-1,4-BENZODIOXIN-2-YL)-4,5-DIHYDRO-1H-IMIDAZOLE HYDROCHLORIDESupplier
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