1-(4-HYDROXYPHENYL)-2-THIOUREA Chemical Properties

Melting point:

214 °C

Boiling point:

341.5±44.0 °C(Predicted)

Density 

1.450±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

pka

9.53±0.26(Predicted)

BRN 

1102429

InChI

InChI=1S/C7H8N2OS/c8-7(11)9-5-1-3-6(10)4-2-5/h1-4,10H,(H3,8,9,11)

InChIKey

QICKOOCQSYZYQB-UHFFFAOYSA-N

SMILES

N(C1=CC=C(O)C=C1)C(N)=S

CAS DataBase Reference

1520-27-0(CAS DataBase Reference)

Safety Information

Risk Statements 

22

Safety Statements 

22-36/37

RTECS 

YT5250000

HazardClass 

IRRITANT

Toxicity

mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689,

MSDS

• Language:English Provider:ALFA

1-(4-HYDROXYPHENYL)-2-THIOUREA Usage And Synthesis

Uses

1-(4-Hydroxyphenyl)thiourea is an intermediate in the synthesis of (SKI II), a nonlipid inhibitor of sphingosine kinase. SKI II s orally bioavailable and has shown significant inhibition of tumor growth in mice.

1-(4-HYDROXYPHENYL)-2-THIOUREA(1520-27-0)Related Product Information

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