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L-SELENOCYSTINE

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L-SELENOCYSTINE Basic information

Product Name:
L-SELENOCYSTINE
Synonyms:
  • SELENO-L-CYSTINE
  • (R,R)-3,3'-DISELENO-BIS(2-AMINOPROPIONIC ACID)
  • L-SELENOCYSTINE
  • 3’-diselenodi-l-alanin
  • l-3,3’-diselenodialanine
  • 3,3'-DISELENO-L-ALANINE
  • L-SELENOCYSTINE 98%
  • (R,R)-3,3μ-Diseleno-bis(2-aminopropionic acid), L-Selenocystine
CAS:
29621-88-3
MF:
C6H12N2O4Se2
MW:
334.09
EINECS:
608-382-6
Product Categories:
  • amino acids
Mol File:
29621-88-3.mol
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L-SELENOCYSTINE Chemical Properties

Melting point:
224.5-229.5 °C (lit.)
Boiling point:
538.3±60.0 °C(Predicted)
storage temp. 
2-8°C
solubility 
Aqueous Acid (Slightly), Aqueous Base (Slightly)
pka
1.69±0.10(Predicted)
form 
Powder
color 
Yellow
optical activity
[α]20/D 28°, c = 1 in NaOH
BRN 
1969559
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
T,N
Risk Statements 
23/25-33-50/53
Safety Statements 
20/21-28-45-60-61
RIDADR 
UN 3283 6.1/PG 3
WGK Germany 
3
RTECS 
AY6032000
HazardClass 
6.1
PackingGroup 
III
HS Code 
29319090

MSDS

  • Language:English Provider:ACROS
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L-SELENOCYSTINE Usage And Synthesis

Description

L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 μM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types.

Chemical Properties

yellow fine powder

Uses

Seleno-L-cystine can be used for the synthesis of:

  • Biologically active selenol compounds.
  • Non-natural selenylated diamino acids.

L-SELENOCYSTINESupplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
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Alabiochem Tech.Co., Ltd.
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0512-58900862 400-0707518
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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isenchem@163.com