Basic information Safety Supplier Related

OMEGA-AGATOXIN TK

Basic information Safety Supplier Related

OMEGA-AGATOXIN TK Basic information

Product Name:
OMEGA-AGATOXIN TK
Synonyms:
  • OMEGA-AGA-IVB
  • OMEGA-AGA-TK
  • OMEGA-AGATOXIN TK
  • OMEGA-AGATOXIN TK, AGELENOPSIS APERTA
  • GLU-ASP-ASN-CYS-ILE-ALA-GLU-ASP-TYR-GLY-LYS-CYS-THR-TRP-GLY-GLY-THR-LYS-CYS-CYS-ARG-GLY-ARG-PRO-CYS-ARG-CYS-SER-MET-ILE-GLY-THR-ASN-CYS-GLU-CYS-THR-PRO-ARG-LEU-ILE-MET-GLU-GLY-LEU-D-SER-PHE-ALA
  • ω-aga-tk
  • ω-agatoxin tk
  • Omega-Agatoxin IVa trifluoroacetate salt H-Lys-Lys-Lys-Cys-Ile-Ala-Lys-Asp-Tyr-Gly-Arg-Cys-Lys-Trp-Gly-Gly-Thr-Pro-Cys-Cys-Arg-Gly-Arg-Gly-Cys-Ile-Cys-Ser-Ile-Met-Gly-Thr-Asn-Cys-Glu-Cys-Lys-Pro-Arg-Leu-Ile-Met-Glu-Gly-Leu-Gly-Leu-Ala-OH trifluoroacetate salt (Disulfide bonds between Cys4 and Cys20/Cys12 and Cys25/Cys19 and Cys36/Cys27 and Cys34)
CAS:
145017-83-0
MF:
C215H337N65O70S10
MW:
5273.02
Product Categories:
  • Ion Channels
  • proteins
Mol File:
Mol File
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OMEGA-AGATOXIN TK Chemical Properties

storage temp. 
-20°C
solubility 
H2O: Aqueous stock solution is stable for 1 month at 2-8°C and for several months at -20°C.soluble
form 
powder
Water Solubility 
Soluble in water
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Safety Information

WGK Germany 
3

MSDS

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OMEGA-AGATOXIN TK Usage And Synthesis

Uses

ω-Agatoxin IVA has been used in the manipulation of calcium influx. It has also been used in the study to characterize the spontaneous and evoked activity from murine ventral horn cultures on microelectrode arrays.

Uses

omega-Agatoxin TK is a selective blocker of the P-type Ca2+?channel.

General Description

CACNA1A (calcium voltage-gated channel subunit alpha1 A)?gene codes for the α1 subunit of neuronal CaV2.1 (P/Q-type) voltage-gated calcium channels. It is expressed throughout the central nervous system (CNS). CACNA1A gene is located on human chromosome 19p13.

Biochem/physiol Actions

Toxin found in the venom of the funnel web spider, Agelenopsis aptera. Potent, selective blocker of mammalian P-type voltage-dependent calcium channels.

storage

-20°C (desiccate)

OMEGA-AGATOXIN TKSupplier

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