1,2,2,6,6-PENTAMETHYLPIPERIDINE Chemical Properties

Melting point:

<25 °C

Boiling point:

187-188 °C(lit.)

Density 

0.858 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.460(lit.)

Flash point:

122 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Soluble in toluene, dimethylformamide.

form 

Liquid

pka

11.25(at 30℃)

color 

Clear colorless to light yellow

Sensitive 

Air Sensitive

Merck 

14,7080

BRN 

103806

InChIKey

XULIXFLCVXWHRF-UHFFFAOYSA-N

CAS DataBase Reference

79-55-0(CAS DataBase Reference)

EPA Substance Registry System

Piperidine, 1,2,2,6,6-pentamethyl- (79-55-0)

Safety Information

Hazard Codes 

Xn

Risk Statements 

10-22-36/37/38

Safety Statements 

26-36/37

RIDADR 

UN 1992 3/PG 3

WGK Germany 

3

RTECS 

TN2190000

F 

10-34

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29333999

Toxicity

LD50 orl-mus: 275 mg/kg NATUAS 184,1707,59

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

1,2,2,6,6-PENTAMETHYLPIPERIDINE Usage And Synthesis

Chemical Properties

CLEAR COLORLESS TO LIGHT YELLOW LIQUID

Uses

ganglionic blocker, antihypertensive

Uses

1,2,2,6,6-Pentamethylpiperidine is used in the synthesis of BN-fused polycyclic aromatic molecules for potential application to electronic materials and apparatus. In addition, it is a catalyst for th e chemoselective silylation of benzylic alcohols.

Uses

Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine's ED50 4.7-fold.

Definition

ChEBI: 1,2,2,6,6-pentamethylpiperidine is a member of piperidines.

General Description

The focal 1,8-naphthalimide fluorophores in the antennae were modified with 1,2,2,6,6-pentamethylpiperidine to improve their photostability.

Safety Profile

Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.

1,2,2,6,6-PENTAMETHYLPIPERIDINE(79-55-0)Related Product Information

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