O-ANISIDINE HYDROCHLORIDE Chemical Properties

Melting point:

228-230 °C

form 

powder to crystal

color 

White to Almost white

Water Solubility 

almost transparency

CAS DataBase Reference

134-29-2(CAS DataBase Reference)

IARC

2A (Vol. 127)

EPA Substance Registry System

o-Anisidine hydrochloride (134-29-2)

Safety Information

Hazard Codes 

Xn

Risk Statements 

36/37/38-22

Safety Statements 

26-36/37/39

RIDADR 

2811

RTECS 

BZ6500000

HS Code 

2922.50.4000

HazardClass 

6.1

PackingGroup 

III

Toxicity

mma-sat 10 mg/plate ENMUDM 7(Suppl 5),1,85

O-ANISIDINE HYDROCHLORIDE Usage And Synthesis

Chemical Properties

Anisidine exists as ortho-, meta-, and paraisomers. They have characteristic amine (fishy) odors.

Uses

o-Anisidine hydrochloride is used as a chemical intermediate in the production of numerous azo and triphenylmethane dyes and pigments (e.g., C.I. direct red 72, disperse orange 29, direct yellow 44, direct red 24, and acid red 4); in the production of pharmaceuticals, including the expectorant guaiacol; as a corrosion inhibitor for steel; and as an antioxidant for polymercaptan resins (IARC 1999, HSDB 2009).

General Description

Gray-black crystalline solid or light gray powder. May be carcinogenic.

Air & Water Reactions

Water soluble.

Reactivity Profile

O-ANISIDINE HYDROCHLORIDE reacts as an acid to neutralize bases. These neutralizations generate some heat, Usually does not react as either oxidizing agents or reducing agents but such behavior is not impossible. May catalyze organic reactions.

Fire Hazard

Flash point data for O-ANISIDINE HYDROCHLORIDE are not available; however, O-ANISIDINE HYDROCHLORIDE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.

Potential Exposure

Anisidines are used in the manufacture of azo dyes; pharmaceuticals; textile-processing chemicals Incompatibilities: Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine,bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Attacks some coatings and some forms of plastic and rubber.

Carcinogenicity

o-Anisidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity in experimental animals.

Shipping

UN2431 Anisidines, Hazard Class: 6.1; Labels: 6.1-Poisonous materials

Waste Disposal

Dissolve in combustible solvent (alcohols, benzene, etc.) and spray solution into furnace equipped with afterburner and scrubber, or burn spill residue on sand and soda ash absorbent in a furnace.

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