ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Phosphine ligand > (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE
(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE
(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE Basic information
- Product Name:
- (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE
- Synonyms:
-
- (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE
- (11AS)-(-)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1-PHENYLETHYL]AMINE
- (S)-SIPHOS-PE
- (R)-SIPHOS-PE
- N-DI[(R)-1-PHENYLETHYL]-[(R)-1,1'-SPIROBIINDANE-7,7'-DIYL]-PHOSPHORAMIDITE
- N-DI[(R)-1-PHENYLETHYL]-[(S)-1,1'-SPIROBIINDANE-7,7'-DIYL]-PHOSPHORAMIDITE
- (11aR)-(+)-10,11,12,13-Tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-bis[(R)-1-phenylethyl]amine,min.98%(R)-SIPHOS-PE
- N-Di[(R)-1-phenylethyl]-[(R)-1,1'-spirobiindane-7,7'-diyl]-phosphoramidite ,98%
- CAS:
- 500997-69-3
- MF:
- C33H32NO2P
- MW:
- 505.59
- Product Categories:
-
- Chiral Phosphine
- Chiral Spiro Ligand
- CPN
- Mol File:
- 500997-69-3.mol
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(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE Chemical Properties
- Melting point:
- 98-100°C
- alpha
- +300° (c 1.0, CH2Cl2)
- Boiling point:
- 617.8±65.0 °C(Predicted)
- storage temp.
- -20°C
- pka
- 0.40±0.20(Predicted)
- form
- solid
- color
- white
- optical activity
- [α]22/D +337°, c = 1 in chloroform
- Sensitive
- moisture sensitive
- InChIKey
- ZXLQLIDJAURBDD-HRPAVAKOSA-N
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(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE Usage And Synthesis
Reaction
- Chiral ligands for copper-catalyzed asymmetric allylic alkylation with dialkylzincs.
- Chiral ligands for copper-catalyzed asymmetric conjugate addition of diethylzinc to enones.
- Chiral ligands for palladium-catalyzed asymmetric hydrosilylation of styrenes
- Chiral ligands for copper-catalyzed asymmetric ring-opening of oxabicyclic alkenes with Grignard reagents.
- Chiral ligands for nickel-catalyzed asymmetric hydrovinylation of α-alkyl vinylarenes.
- Chiral ligands for iridium-catalyzed asymmetric hydrogenation of cyclic enamines.
- Chiral ligands for iridium-catalyzed asymmetric hydrogenation of cyclic imines.
- Chiral ligands for gold-catalyzed asymmetric [2 + 2] cycloaddition reaction.
- Chiral ligands for rhodium-catalyzed asymmetric hydroacylation of salicylaldehydes to homoallylic sulfides.
- Chiral ligands for palladium-catalyzed asymmetric carboamination reactions.
Uses
(R)-SIPHOS-PE can be used as:
- A catalyst in the preparation of tricyclic alkaloid (+)-aphanorphine via asymmetric carboamination and Friedel?Crafts reaction.
- A ligand in the synthesis of chiral ketones via hydroacylation of olefins using salicylaldehyde derivatives.
- A ligand in the enantioselective synthesis of substituted pyrrolidine derivatives via Pd-catalyzed alkene aminoarylation reactions.
(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE Preparation Products And Raw materials
Raw materials
EtanolSodium hydroxideHydrochloric acidEthyl acetateTetrahydrofuranDichloromethanePETROLEUM ETHERTolueneTriethylamineSodium chlorideAcetonen-ButyllithiumSodium bicarbonateHydrogen peroxidePalladiumHydrogenPhosphorus trichlorideNickelBenzyl chlorideEthyldiisopropylamineSodium bromideMethanesulfonic acidBoron tribromide3-Hydroxybenzaldehyde(R)-1,1'-SPIROBIINDANE-7,7'-DIOLCinchonidineCALCIUM HYDRIDE(R,R)-(+)-BIS(ALPHA-METHYLBENZYL)AMINE HYDROCHLORIDE(R,R)-(+)-BIS(ALPHA-METHYLBENZYL)AMINE HYDROCHLORIDE
(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINESupplier
J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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- 021-61259108 18621169109
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BeiJing Hwrk Chemicals Limted
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- 0757-86329057 18934348241
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Daicel Chiral Technologies (China)CO.,LTD
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- 021-50460086-9 15921403865
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Tianjin Derchemist Science & Technology Co., Ltd.
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- 22-58627059 13920586291
- zdcomcon@126.com
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(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE(500997-69-3)Related Product Information
- (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE
- 3A,4,7,7A-TETRAHYDROINDENE
- (R,R)-(+)-BIS(ALPHA-METHYLBENZYL)AMINE HYDROCHLORIDE
- (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE
- (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-DIMETHYLAMINE